ADHDgene Database

Gene Report

Basic Info

Approved Symbol	AP4S1
Symbol Alias	CLA20, AP47B
Approved Name	adaptor-related protein complex 4, sigma 1 subunit
Location	14q12
Position	chr14:31494683-31562638, +
External Links	HGNC: 575 Entrez Gene: 11154 Ensembl: ENSG00000100478 UCSC: uc001wqw.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
14q12	chr14:24600000-33300000	1 (1/0/0)

Gene related GO terms (count: 4)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005794	Golgi apparatus	Cellular Component		157
GO:0005215	transporter activity	Molecular Function	TAS[10436028]	41
GO:0008565	protein transporter activity	Molecular Function		11
GO:0005905	coated pit	Cellular Component		8

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04142	Lysosome	19	Lysosomes are membrane-delimited organelles in animal cells ...... Lysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than 40 hydrolases in an acidic environment (pH of about 5). After synthesis in the ER, lysosomal enzymes are decorated with mannose-6-phosphate residues, which are recognized by mannose-6-phosphate receptors in the trans-Golgi network. They are packaged into clathrin-coated vesicles and are transported to late endosomes. Substances for digestion are acquired by the lysosomes via a series of processes including endocytosis, phagocytosis, and autophagy. More...

Genes shared at least 5 GO terms with AP4S1 (count: 0)

Genes shared at least 2 KEGG pathways with AP4S1 (count: 0)

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Region: chr14:31494683..31562638 View in gBrowse