ADHDgene Database

Gene Report

Basic Info

Approved Symbol	BTG4
Symbol Alias	PC3B
Approved Name	B-cell translocation gene 4
Location	11q23
Position	chr11:111338251-111383079, -
External Links	HGNC: 13862 Entrez Gene: 54766 Ensembl: ENSG00000137707 UCSC: uc001plj.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 5)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005575	cellular_component	Cellular Component		98
GO:0008285	negative regulation of cell proliferation	Biological Process	TAS[10995567]	59
GO:0007050	cell cycle arrest	Biological Process	TAS[10995567]	25
GO:0045930	negative regulation of mitotic cell cycle	Biological Process		2
GO:0030182	neuron differentiation	Biological Process	TAS[10995567]	9

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa03018	RNA degradation	8	The correct processing, quality control and turnover of cell...... The correct processing, quality control and turnover of cellular RNA molecules are critical to many aspects in the expression of genetic information. In eukaryotes, two major pathways of mRNA decay exist and both pathways are initiated by poly(A) shortening of the mRNA. In the 5' to 3' pathway, this is followed by decapping which then permits the 5' to 3' exonucleolytic degradation of transcripts. In the 3' to 5' pathway, the exosome, a large multisubunit complex, plays a key role. The exosome exists in archaeal cells, too. In bacteria, endoribonuclease E, a key enzyme involved in RNA decay and processing, organizes a protein complex called degradosome. RNase E or R interacts with the phosphate-dependent exoribonuclease polynucleotide phosphorylase, DEAD-box helicases, and additional factors in the RNA-degrading complex. More...

Genes shared at least 5 GO terms with BTG4 (count: 0)

Genes shared at least 2 KEGG pathways with BTG4 (count: 0)

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Region: chr11:111338251..111383079 View in gBrowse