ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CCDC88A
Previous Symbol	KIAA1212
Symbol Alias	FLJ10392, APE, GIV, HkRP1, GRDN
Approved Name	coiled-coil domain containing 88A
Previous Name	KIAA1212
Name Alias	Galpha-interacting vesicle-associated protein, "Akt-phosphorylation enhancer", "girdin"
Location	2p16.3
Position	chr2:55514978-55647057, -
External Links	HGNC: 25523 Entrez Gene: 55704 Ensembl: ENSG00000115355 UCSC: uc002ryv.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 26)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 2)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process		39
GO:0051493	regulation of cytoskeleton organization	Biological Process		32

GO terms by database search (count: 24)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006275	regulation of DNA replication	Biological Process		3
GO:0008017	microtubule binding	Molecular Function		32
GO:0005886	plasma membrane	Cellular Component	IDA[15882442]	772
GO:0006260	DNA replication	Biological Process		27
GO:0016023	cytoplasmic membrane-bounded vesicle	Cellular Component		16
GO:0016044	cellular membrane organization	Biological Process	IDA[15882442]	24
GO:0010975	regulation of neuron projection development	Biological Process		1
GO:0016020	membrane	Cellular Component	IDA[15749703]	139
GO:0001932	regulation of protein phosphorylation	Biological Process		4
GO:0005794	Golgi apparatus	Cellular Component	IDA[15882442]	157
GO:0005829	cytosol	Cellular Component	IDA[15749703]	447
GO:0003779	actin binding	Molecular Function	IDA[16139227]	46
GO:0005783	endoplasmic reticulum	Cellular Component	IDA[15882442]	100
GO:0043422	protein kinase B binding	Molecular Function	IPI[16139227]	3
GO:0042803	protein homodimerization activity	Molecular Function	IPI[16139227]	113
GO:0042127	regulation of cell proliferation	Biological Process		20
GO:0031410	cytoplasmic vesicle	Cellular Component	IDA[15882442]	20
GO:0030032	lamellipodium assembly	Biological Process	IMP[16139227]	8
GO:0030027	lamellipodium	Cellular Component	IDA[16139227]	27
GO:0016477	cell migration	Biological Process	IMP[16139227]	24
GO:0035091	phosphatidylinositol binding	Molecular Function	IDA[16139227]	13
GO:0032956	regulation of actin cytoskeleton organization	Biological Process	IMP[16139227]	6
GO:0032148	activation of protein kinase B activity	Biological Process		6
GO:0031929	TOR signaling cascade	Biological Process		3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with CCDC88A (count: 16)

Gene Symbol	Pathway Count	Pathway List
APC	7	microtubule binding; plasma membrane; microtubule cytoskeleton organization; cytosol; regulation of cytoskeleton organization; lamellipodium; cell migration;
ARHGEF2	6	microtubule binding; microtubule cytoskeleton organization; Golgi apparatus; cytosol; regulation of cytoskeleton organization; regulation of cell proliferation;
CUBN	6	plasma membrane; membrane; Golgi apparatus; cytosol; endoplasmic reticulum; protein homodimerization activity;
NCK1	6	plasma membrane; cytosol; endoplasmic reticulum; regulation of cytoskeleton organization; lamellipodium assembly; cell migration;
FES	6	cytoplasmic membrane-bounded vesicle; Golgi apparatus; cytosol; regulation of cell proliferation; cytoplasmic vesicle; phosphatidylinositol binding;
CLASP1	5	microtubule binding; microtubule cytoskeleton organization; Golgi apparatus; cytosol; regulation of cytoskeleton organization;
CRYAB	5	microtubule binding; plasma membrane; Golgi apparatus; cytosol; protein homodimerization activity;
MAPT	5	microtubule binding; plasma membrane; microtubule cytoskeleton organization; cytosol; regulation of cytoskeleton organization;
ACHE	5	plasma membrane; DNA replication; membrane; Golgi apparatus; protein homodimerization activity;
ARRB2	5	plasma membrane; cytoplasmic membrane-bounded vesicle; cytosol; protein kinase B binding; cytoplasmic vesicle;
CLASP2	5	plasma membrane; microtubule cytoskeleton organization; Golgi apparatus; cytosol; regulation of cytoskeleton organization;
CTGF	5	plasma membrane; DNA replication; Golgi apparatus; cytosol; cell migration;
INPPL1	5	plasma membrane; Golgi apparatus; cytosol; actin binding; lamellipodium;
PDE2A	5	plasma membrane; Golgi apparatus; cytosol; endoplasmic reticulum; protein homodimerization activity;
WASL	5	plasma membrane; cytoplasmic membrane-bounded vesicle; cytosol; actin binding; lamellipodium;
NCK2	5	cytosol; endoplasmic reticulum; regulation of cytoskeleton organization; lamellipodium assembly; cell migration;

Genes shared at least 2 KEGG pathways with CCDC88A (count: 0)

View in gBrowse

Region: chr2:55514978..55647057 View in gBrowse