ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	COPB1
Previous Symbol	COPB
Approved Name	coatomer protein complex, subunit beta 1
Previous Name	coatomer protein complex, subunit beta
Location	11p15.2
Position	chr11:14464986-14521573, -
External Links	HGNC: 2231 Entrez Gene: 1315 Ensembl: ENSG00000129083 UCSC: uc001mlg.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048193	Golgi vesicle transport	Biological Process		49

GO terms by database search (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0030126	COPI vesicle coat	Cellular Component		8
GO:0019048	virus-host interaction	Biological Process		54
GO:0016044	cellular membrane organization	Biological Process		24
GO:0006891	intra-Golgi vesicle-mediated transport	Biological Process		13
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	Biological Process		16
GO:0006886	intracellular protein transport	Biological Process		43
GO:0005886	plasma membrane	Cellular Component		772
GO:0005829	cytosol	Cellular Component		447
GO:0005798	Golgi-associated vesicle	Cellular Component	TAS[1840503]	5
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	Cellular Component		17
GO:0005515	protein binding	Molecular Function	IPI[18556652]	910
GO:0005198	structural molecule activity	Molecular Function		29
GO:0000139	Golgi membrane	Cellular Component	TAS[1840503]	95
GO:0048205	COPI coating of Golgi vesicle	Biological Process		8

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with COPB1 (count: 17)

Gene Symbol	Pathway Count	Pathway List
COPB2	9	COPI vesicle coat; cellular membrane organization; intra-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; cytosol; structural molecule activity; Golgi vesicle transport; COPI coating of Golgi vesicle;
COPE	8	COPI vesicle coat; cellular membrane organization; intra-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER; cytosol; structural molecule activity; Golgi vesicle transport; COPI coating of Golgi vesicle;
COPZ1	8	COPI vesicle coat; cellular membrane organization; intra-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; cytosol; Golgi vesicle transport; COPI coating of Golgi vesicle;
TMED10	7	retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; plasma membrane; endoplasmic reticulum-Golgi intermediate compartment; protein binding; Golgi vesicle transport; COPI coating of Golgi vesicle;
ARCN1	6	COPI vesicle coat; cellular membrane organization; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; cytosol; COPI coating of Golgi vesicle;
COPG2	6	COPI vesicle coat; intra-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; structural molecule activity; Golgi vesicle transport;
NAPA	6	cellular membrane organization; intra-Golgi vesicle-mediated transport; intracellular protein transport; cytosol; protein binding; Golgi vesicle transport;
COG3	6	intra-Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; plasma membrane; protein binding; Golgi vesicle transport;
HSPA8	5	virus-host interaction; cellular membrane organization; plasma membrane; cytosol; protein binding;
ARRB1	5	cellular membrane organization; plasma membrane; cytosol; protein binding; Golgi membrane;
GBF1	5	cellular membrane organization; retrograde vesicle-mediated transport, Golgi to ER; Golgi membrane; Golgi vesicle transport; COPI coating of Golgi vesicle;
STX4	5	cellular membrane organization; intracellular protein transport; plasma membrane; cytosol; protein binding;
COG2	5	intra-Golgi vesicle-mediated transport; intracellular protein transport; protein binding; Golgi membrane; Golgi vesicle transport;
STX16	5	intra-Golgi vesicle-mediated transport; intracellular protein transport; protein binding; Golgi membrane; Golgi vesicle transport;
COG7	5	retrograde vesicle-mediated transport, Golgi to ER; intracellular protein transport; protein binding; Golgi membrane; Golgi vesicle transport;
STX6	5	intracellular protein transport; plasma membrane; protein binding; Golgi membrane; Golgi vesicle transport;
RAB14	5	plasma membrane; cytosol; protein binding; Golgi membrane; Golgi vesicle transport;

Genes shared at least 2 KEGG pathways with COPB1 (count: 0)

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Region: chr11:14464986..14521573 View in gBrowse