ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ELOVL6
Symbol Alias	FLJ23378, MGC5487, LCE
Approved Name	ELOVL fatty acid elongase 6
Previous Name	ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast)
Location	4q25
Position	chr4:110967002-111120355, -
External Links	HGNC: 15829 Entrez Gene: 79071 Ensembl: ENSG00000170522 UCSC: uc003hzz.2
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Mick E, 2010	Trend associated SNP was mapped in this gene.	Trend

Gene related SNPs (count: 9)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs10011926	Chr4:111026927(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs3733623	Chr4:111026520(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs10032613	Chr4:111021758(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs7669237	Chr4:111020741(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs4698810	Chr4:111019636(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs1482469	Chr4:111031236(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs10033229	Chr4:111030075(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs718815	Chr4:111024520(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant
rs10018930	Chr4:111029635(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 11)

ID	Name	Type	No. of Genes in ADHDgene
GO:0030176	integral to endoplasmic reticulum membrane	Cellular Component	14
GO:0035338	long-chain fatty-acyl-CoA biosynthetic process	Biological Process	4
GO:0019367	fatty acid elongation, saturated fatty acid	Biological Process	2
GO:0019432	triglyceride biosynthetic process	Biological Process	12
GO:0044281	small molecule metabolic process	Biological Process	248
GO:0042759	long-chain fatty acid biosynthetic process	Biological Process	1
GO:0044255	cellular lipid metabolic process	Biological Process	30
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	Molecular Function	2
GO:0005789	endoplasmic reticulum membrane	Cellular Component	140
GO:0005783	endoplasmic reticulum	Cellular Component	100
GO:0005515	protein binding	Molecular Function	910

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01040	Biosynthesis of unsaturated fatty acids	5

Genes shared at least 5 GO terms with ELOVL6 (count: 4)

Gene Symbol	Pathway Count	Pathway List
ELOVL7	8	long-chain fatty-acyl-CoA biosynthetic process; fatty acid elongation, saturated fatty acid; triglyceride biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; endoplasmic reticulum membrane; endoplasmic reticulum; protein binding;
DGAT2	6	integral to endoplasmic reticulum membrane; triglyceride biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; endoplasmic reticulum membrane; endoplasmic reticulum;
ACACA	5	long-chain fatty-acyl-CoA biosynthetic process; triglyceride biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; protein binding;
LPCAT1	5	triglyceride biosynthetic process; small molecule metabolic process; cellular lipid metabolic process; endoplasmic reticulum membrane; endoplasmic reticulum;

Genes shared at least 2 KEGG pathways with ELOVL6 (count: 0)

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Region: chr4:110967002..111120355 View in gBrowse