ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FYB
Symbol Alias	SLAP-130, FYB-120/130
Approved Name	FYN binding protein
Previous Name	FYN-binding protein (FYB-120/130)
Location	5p13.1
Position	chr5:39105338-39274630, -
External Links	HGNC: 4036 Entrez Gene: 2533 Ensembl: ENSG00000082074 UCSC: uc003jlt.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
5p13	chr5:28900000-42500000	3 (1/1/1)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0032403	protein complex binding	Molecular Function		27
GO:0050852	T cell receptor signaling pathway	Biological Process		21
GO:0006955	immune response	Biological Process	TAS[9207119]	45
GO:0006607	NLS-bearing substrate import into nucleus	Biological Process	TAS[9207119]	2
GO:0006468	protein phosphorylation	Biological Process	TAS[9207119]	53
GO:0005829	cytosol	Cellular Component		447
GO:0015629	actin cytoskeleton	Cellular Component	TAS[10747096]	26
GO:0008150	biological_process	Biological Process		106
GO:0007243	intracellular protein kinase cascade	Biological Process	TAS[9207119]	19
GO:0007165	signal transduction	Biological Process	TAS[9207119]	171
GO:0005634	nucleus	Cellular Component		770
GO:0005515	protein binding	Molecular Function		910
GO:0005102	receptor binding	Molecular Function	TAS[10747096]	61

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FYB (count: 10)

Gene Symbol	Pathway Count	Pathway List
ARRB2	5	protein complex binding; cytosol; nucleus; protein binding; receptor binding;
RELA	5	protein complex binding; T cell receptor signaling pathway; cytosol; nucleus; protein binding;
UFD1L	5	protein complex binding; cytosol; nucleus; protein binding; receptor binding;
MAPK1	5	T cell receptor signaling pathway; cytosol; signal transduction; nucleus; protein binding;
NCK1	5	T cell receptor signaling pathway; cytosol; nucleus; protein binding; receptor binding;
CSNK1E	5	protein phosphorylation; cytosol; signal transduction; nucleus; protein binding;
LATS2	5	protein phosphorylation; cytosol; intracellular protein kinase cascade; nucleus; protein binding;
PRKAA1	5	protein phosphorylation; cytosol; signal transduction; nucleus; protein binding;
PRKCB	5	protein phosphorylation; cytosol; signal transduction; nucleus; protein binding;
PRKD1	5	cytosol; intracellular protein kinase cascade; signal transduction; nucleus; protein binding;

Genes shared at least 2 KEGG pathways with FYB (count: 0)

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Region: chr5:39105338..39274630 View in gBrowse