ADHDgene Database

Gene Report

Basic Info

Approved Symbol	INVS
Previous Symbol	NPHP2
Approved Name	inversin
Previous Name	nephronophthisis 2 (infantile)
Location	9q31
Position	chr9:102861511-103063426, +
External Links	HGNC: 17870 Entrez Gene: 27130 Ensembl: ENSG00000119509 UCSC: uc004bap.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001822	kidney development	Biological Process		16
GO:0005516	calmodulin binding	Molecular Function		32
GO:0005515	protein binding	Molecular Function		910
GO:0005737	cytoplasm	Cellular Component		690
GO:0005634	nucleus	Cellular Component		770
GO:0005874	microtubule	Cellular Component		52
GO:0005819	spindle	Cellular Component		29
GO:0009791	post-embryonic development	Biological Process		16
GO:0005929	cilium	Cellular Component		18
GO:0090090	negative regulation of canonical Wnt receptor signaling pathway	Biological Process	IDA[18371931]	14
GO:0031016	pancreas development	Biological Process		5
GO:0060971	embryonic heart tube left/right pattern formation	Biological Process		1
GO:0016020	membrane	Cellular Component		139
GO:0016055	Wnt receptor signaling pathway	Biological Process		20

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with INVS (count: 4)

Gene Symbol	Pathway Count	Pathway List
APC	5	kidney development; protein binding; cytoplasm; nucleus; negative regulation of canonical Wnt receptor signaling pathway;
PYGO1	5	kidney development; protein binding; nucleus; post-embryonic development; Wnt receptor signaling pathway;
CTNND1	5	protein binding; cytoplasm; nucleus; negative regulation of canonical Wnt receptor signaling pathway; Wnt receptor signaling pathway;
DACT1	5	protein binding; cytoplasm; nucleus; negative regulation of canonical Wnt receptor signaling pathway; Wnt receptor signaling pathway;

Genes shared at least 2 KEGG pathways with INVS (count: 0)

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Region: chr9:102861511..103063426 View in gBrowse