ADHDgene Database

Gene Report

Basic Info

Approved Symbol	KCTD13
Symbol Alias	PDIP1, FKSG86, POLDIP1
Approved Name	potassium channel tetramerisation domain containing 13
Name Alias	polymerase delta-interacting protein 1, "TNFAIP1-like"
Location	16p11.2
Position	chr16:29917657-29937549, -
External Links	HGNC: 22234 Entrez Gene: 253980 Ensembl: ENSG00000174943 UCSC: uc002duv.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 4)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_16	chr16:29563594-30367556 (NCBI Build 36.1 (hg18))	803963	16p11.2	Loss
CNV_Williams[2010]_34	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813248	16p11.2	Loss	De novo
CNV_Williams[2010]_39	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813247	16p11.2	Gain
CNV_Jarick[2012]_35	chr16:29554843-30085308 (NCBI36 / hg18)	530466	16p11.2	del

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006260	DNA replication	Biological Process	ISS[15726626]	27
GO:0005634	nucleus	Cellular Component		770
GO:0004842	ubiquitin-protein ligase activity	Molecular Function	IDA[19782033]	52
GO:0051260	protein homooligomerization	Biological Process		34
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	Biological Process	IDA[19782033]	16
GO:0045740	positive regulation of DNA replication	Biological Process		7
GO:0042802	identical protein binding	Molecular Function		70
GO:0043149	stress fiber assembly	Biological Process	IMP[19782033]	2
GO:0031463	Cul3-RING ubiquitin ligase complex	Cellular Component	IDA[19782033]	5
GO:0035024	negative regulation of Rho protein signal transduction	Biological Process	IMP[19782033]	4
GO:0017049	GTP-Rho binding	Molecular Function	IDA[19782033]	3
GO:0019904	protein domain specific binding	Molecular Function		40
GO:0016477	cell migration	Biological Process	IMP[19782033]	24
GO:0016567	protein ubiquitination	Biological Process	IDA[19782033]	41

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with KCTD13 (count: 1)

Gene Symbol	Pathway Count	Pathway List
KLHL20	5	nucleus; ubiquitin-protein ligase activity; proteasomal ubiquitin-dependent protein catabolic process; Cul3-RING ubiquitin ligase complex; protein ubiquitination;

Genes shared at least 2 KEGG pathways with KCTD13 (count: 0)

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Region: chr16:29917657..29937549 View in gBrowse