ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	KIF11
Previous Symbol	KNSL1
Symbol Alias	Eg5, HKSP, TRIP5
Approved Name	kinesin family member 11
Previous Name	kinesin-like 1
Location	10q24.1
Position	chr10:94352825-94415152, +
External Links	HGNC: 6388 Entrez Gene: 3832 Ensembl: ENSG00000138160 UCSC: uc001kic.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 21)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000226	microtubule cytoskeleton organization	Biological Process		39

GO terms by database search (count: 20)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000922	spindle pole	Cellular Component	IDA[14718566]	22
GO:0003777	microtubule motor activity	Molecular Function		17
GO:0005524	ATP binding	Molecular Function		228
GO:0005737	cytoplasm	Cellular Component		690
GO:0005819	spindle	Cellular Component	IDA[19001501]	29
GO:0005829	cytosol	Cellular Component		447
GO:0005871	kinesin complex	Cellular Component	TAS[8548803]	5
GO:0005874	microtubule	Cellular Component		52
GO:0005876	spindle microtubule	Cellular Component	IDA[14718566]	9
GO:0007018	microtubule-based movement	Biological Process		20
GO:0007051	spindle organization	Biological Process	IMP[14718566]	5
GO:0007052	mitotic spindle organization	Biological Process	TAS[8548803]	7
GO:0007100	mitotic centrosome separation	Biological Process		1
GO:0007067	mitosis	Biological Process	TAS[8548803]	39
GO:0008017	microtubule binding	Molecular Function		32
GO:0007596	blood coagulation	Biological Process		83
GO:0019901	protein kinase binding	Molecular Function	IPI[19001501]	51
GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II	Biological Process		14
GO:0090307	spindle assembly involved in mitosis	Biological Process	IDA[19001501]	1
GO:0051301	cell division	Biological Process		58

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with KIF11 (count: 37)

Gene Symbol	Pathway Count	Pathway List
KIF23	11	microtubule cytoskeleton organization; microtubule motor activity; ATP binding; spindle; cytosol; kinesin complex; microtubule; microtubule-based movement; microtubule binding; blood coagulation; antigen processing and presentation of exogenous peptide antigen via MHC class II;
KIF2C	10	microtubule cytoskeleton organization; microtubule motor activity; ATP binding; cytosol; kinesin complex; microtubule-based movement; mitosis; blood coagulation; antigen processing and presentation of exogenous peptide antigen via MHC class II; cell division;
KIF22	10	microtubule motor activity; ATP binding; cytoplasm; spindle; cytosol; microtubule; microtubule-based movement; mitosis; blood coagulation; antigen processing and presentation of exogenous peptide antigen via MHC class II;
SMC3	8	microtubule cytoskeleton organization; spindle pole; microtubule motor activity; ATP binding; cytoplasm; mitotic spindle organization; mitosis; cell division;
PLK1	8	spindle pole; ATP binding; spindle; cytosol; spindle microtubule; mitosis; microtubule binding; protein kinase binding;
ARHGEF2	7	microtubule cytoskeleton organization; spindle; cytosol; microtubule; mitosis; microtubule binding; cell division;
CDK5RAP2	7	microtubule cytoskeleton organization; spindle pole; cytoplasm; cytosol; microtubule; microtubule binding; protein kinase binding;
KATNB1	7	microtubule cytoskeleton organization; spindle pole; cytoplasm; microtubule; mitosis; microtubule binding; cell division;
PRC1	7	microtubule cytoskeleton organization; spindle pole; cytoplasm; spindle; spindle microtubule; microtubule binding; protein kinase binding;
PSRC1	7	spindle pole; cytoplasm; spindle; cytosol; spindle microtubule; microtubule binding; cell division;
KIFC1	7	microtubule motor activity; ATP binding; spindle; microtubule; microtubule-based movement; blood coagulation; cell division;
KLC2	7	microtubule motor activity; cytosol; kinesin complex; microtubule; microtubule-based movement; blood coagulation; antigen processing and presentation of exogenous peptide antigen via MHC class II;
MAPRE1	6	microtubule cytoskeleton organization; cytoplasm; spindle; cytosol; microtubule; cell division;
RAN	6	microtubule cytoskeleton organization; cytoplasm; cytosol; mitotic spindle organization; mitosis; cell division;
SMC1A	6	microtubule cytoskeleton organization; microtubule motor activity; ATP binding; cytoplasm; mitotic spindle organization; cell division;
LATS1	6	spindle pole; ATP binding; cytosol; mitosis; protein kinase binding; cell division;
NEK6	6	spindle pole; ATP binding; cytoplasm; microtubule; mitosis; protein kinase binding;
NUMA1	6	spindle pole; cytoplasm; spindle; cytosol; spindle microtubule; cell division;
DYNC2H1	6	microtubule motor activity; ATP binding; cytosol; microtubule; microtubule-based movement; antigen processing and presentation of exogenous peptide antigen via MHC class II;
APC	5	microtubule cytoskeleton organization; cytoplasm; cytosol; microtubule binding; protein kinase binding;
CENPJ	5	microtubule cytoskeleton organization; cytosol; microtubule; protein kinase binding; cell division;
CKAP5	5	microtubule cytoskeleton organization; spindle pole; cytosol; spindle organization; cell division;
CLASP1	5	microtubule cytoskeleton organization; cytosol; spindle microtubule; microtubule binding; cell division;
CLASP2	5	microtubule cytoskeleton organization; cytoplasm; cytosol; microtubule; cell division;
MAP1S	5	microtubule cytoskeleton organization; spindle; cytosol; microtubule; microtubule binding;
MAPT	5	microtubule cytoskeleton organization; cytosol; microtubule; microtubule binding; protein kinase binding;
PAFAH1B1	5	microtubule cytoskeleton organization; cytoplasm; cytosol; kinesin complex; microtubule binding;
RCC1	5	microtubule cytoskeleton organization; cytoplasm; mitotic spindle organization; mitosis; cell division;
TTK	5	microtubule cytoskeleton organization; ATP binding; spindle; spindle organization; mitotic spindle organization;
TUBGCP5	5	microtubule cytoskeleton organization; spindle pole; cytosol; microtubule; microtubule binding;
TUBGCP6	5	microtubule cytoskeleton organization; spindle pole; cytosol; microtubule; microtubule binding;
CDC25B	5	spindle pole; cytosol; mitosis; protein kinase binding; cell division;
LATS2	5	spindle pole; ATP binding; cytosol; mitosis; cell division;
KIF12	5	microtubule motor activity; ATP binding; cytoplasm; microtubule; microtubule-based movement;
MAPK1	5	ATP binding; cytoplasm; spindle; cytosol; blood coagulation;
BCAR1	5	cytoplasm; cytosol; blood coagulation; protein kinase binding; cell division;
MAPRE2	5	cytoplasm; microtubule; mitosis; microtubule binding; cell division;

Genes shared at least 2 KEGG pathways with KIF11 (count: 0)

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Region: chr10:94352825..94415152 View in gBrowse