ADHDgene Database

Gene Report

Basic Info

Approved Symbol	LIMA1
Symbol Alias	EPLIN
Approved Name	LIM domain and actin binding 1
Name Alias	epithelial protein lost in neoplasm beta
Location	12q13.12
Position	chr12:50569563-50677353, -
External Links	HGNC: 24636 Entrez Gene: 51474 Ensembl: ENSG00000050405 UCSC: uc001rwk.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0051493	regulation of cytoskeleton organization	Biological Process		32

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001725	stress fiber	Cellular Component	IDA[10618726]	3
GO:0005886	plasma membrane	Cellular Component		772
GO:0005925	focal adhesion	Cellular Component	IDA[10618726]	26
GO:0003785	actin monomer binding	Molecular Function	IDA[12566430]	2
GO:0005737	cytoplasm	Cellular Component		690
GO:0030835	negative regulation of actin filament depolymerization	Biological Process	IDA[12566430]	2
GO:0031529	ruffle organization	Biological Process	IDA[12566430]	5
GO:0008270	zinc ion binding	Molecular Function		323
GO:0015629	actin cytoskeleton	Cellular Component		26
GO:0051015	actin filament binding	Molecular Function	IDA[12566430]	14
GO:0051017	actin filament bundle assembly	Biological Process	IDA[12566430]	3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with LIMA1 (count: 1)

Gene Symbol	Pathway Count	Pathway List
ADAM17	5	plasma membrane; focal adhesion; cytoplasm; zinc ion binding; actin cytoskeleton;

Genes shared at least 2 KEGG pathways with LIMA1 (count: 0)

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Region: chr12:50569563..50677353 View in gBrowse