ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MED1
Previous Symbol	TRIP2, PPARGBP, PPARBP
Symbol Alias	PBP, TRAP220, RB18A, DRIP230, CRSP200, CRSP1
Approved Name	mediator complex subunit 1
Previous Name	PPAR binding protein
Location	17q12
Position	chr17:37560538-37607527, -
External Links	HGNC: 9234 Entrez Gene: 5469 Ensembl: ENSG00000125686 UCSC: uc002hrv.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy; Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 2)

Literature-origin SNPs (count: 0)

LD-proxies (count: 2)

rs_ID	Location	Functional Annotation
rs9646419	Chr17:37597185(Fwd)	NMD_transcript_variant; downstream_gene_variant; intron_variant
rs12150047	Chr17:37601755(Fwd)	NMD_transcript_variant; intron_variant; missense_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 82)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0035257	nuclear hormone receptor binding	Molecular Function		30

GO terms by database search (count: 81)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:2001141	regulation of RNA biosynthetic process	Biological Process	IMP[17223341]	2
GO:2000273	positive regulation of receptor activity	Biological Process	IMP[18391015]	3
GO:2000347	positive regulation of hepatocyte proliferation	Biological Process		2
GO:0071383	cellular response to steroid hormone stimulus	Biological Process	IDA[18391015]	2
GO:0097067	cellular response to thyroid hormone stimulus	Biological Process	IDA[18391015]	1
GO:0070562	regulation of vitamin D receptor signaling pathway	Biological Process		2
GO:0071364	cellular response to epidermal growth factor stimulus	Biological Process	IDA[16314496]	3
GO:0048822	enucleate erythrocyte development	Biological Process		1
GO:0048821	erythrocyte development	Biological Process		1
GO:0046966	thyroid hormone receptor binding	Molecular Function	IDA[10198638]; IPI[9653119]	18
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	Biological Process	IDA[12037571]; IMP[17641689]	131
GO:0045893	positive regulation of transcription, DNA-dependent	Biological Process	IDA[10198638]	80
GO:0045665	negative regulation of neuron differentiation	Biological Process		13
GO:0045618	positive regulation of keratinocyte differentiation	Biological Process	IMP[17082781]	1
GO:0045444	fat cell differentiation	Biological Process	IDA[12037571]	9
GO:0070371	ERK1 and ERK2 cascade	Biological Process	IDA[18391015]	7
GO:0070318	positive regulation of G0 to G1 transition	Biological Process		2
GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation	Biological Process		1
GO:0060745	mammary gland branching involved in pregnancy	Biological Process		1
GO:0060744	mammary gland branching involved in thelarche	Biological Process		1
GO:0060335	positive regulation of interferon-gamma-mediated signaling pathway	Biological Process		2
GO:0051726	regulation of cell cycle	Biological Process	NAS[16314496]	8
GO:0050693	LBD domain binding	Molecular Function	IPI[17827210]	1
GO:0033601	positive regulation of mammary gland epithelial cell proliferation	Biological Process		2
GO:0035050	embryonic heart tube development	Biological Process		3
GO:0035116	embryonic hindlimb morphogenesis	Biological Process		3
GO:0035162	embryonic hemopoiesis	Biological Process		4
GO:0035357	peroxisome proliferator activated receptor signaling pathway	Biological Process		1
GO:0035729	cellular response to hepatocyte growth factor stimulus	Biological Process		3
GO:0035855	megakaryocyte development	Biological Process		2
GO:0036033	mediator complex binding	Molecular Function	IDA[18391015]	4
GO:0042789	mRNA transcription from RNA polymerase II promoter	Biological Process		1
GO:0042809	vitamin D receptor binding	Molecular Function	IPI[9653119]; NAS[10235266]; TAS[17223341]	11
GO:0042974	retinoic acid receptor binding	Molecular Function	IPI[9653119]	4
GO:0042975	peroxisome proliferator activated receptor binding	Molecular Function	IPI[9653119]	3
GO:0043066	negative regulation of apoptotic process	Biological Process		77
GO:0044255	cellular lipid metabolic process	Biological Process		30
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0010467	gene expression	Biological Process		140
GO:0008134	transcription factor binding	Molecular Function	IPI[17641689]	38
GO:0010839	negative regulation of keratinocyte proliferation	Biological Process	IMP[17223341]	2
GO:0010628	positive regulation of gene expression	Biological Process	IDA[17827210]; IMP[17223341]	28
GO:0016922	ligand-dependent nuclear receptor binding	Molecular Function	IDA[18391015]; IPI[9653119]	4
GO:0016592	mediator complex	Cellular Component	IDA[14638676]; IMP[17641689]	17
GO:0030224	monocyte differentiation	Biological Process		3
GO:0030216	keratinocyte differentiation	Biological Process	IMP[17223341]	9
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity	Molecular Function	IMP[17641689]; NAS[10235266]	19
GO:0030331	estrogen receptor binding	Molecular Function	IPI[9653119]	10
GO:0030518	intracellular steroid hormone receptor signaling pathway	Biological Process	IDA[11867769]	10
GO:0030375	thyroid hormone receptor coactivator activity	Molecular Function	IMP[18391015]	2
GO:0031100	organ regeneration	Biological Process		11
GO:0030521	androgen receptor signaling pathway	Biological Process	IDA[12218053]	16
GO:0033160	positive regulation of protein import into nucleus, translocation	Biological Process		3
GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway	Biological Process		3
GO:0003712	transcription cofactor activity	Molecular Function	IDA[12218053]	17
GO:0003713	transcription coactivator activity	Molecular Function	IDA[12037571]; IMP[17223341]	52
GO:0003406	retinal pigment epithelium development	Biological Process		2
GO:0003682	chromatin binding	Molecular Function	IMP[17641689]	48
GO:0005634	nucleus	Cellular Component	IDA[10235267]	770
GO:0005654	nucleoplasm	Cellular Component		183
GO:0004872	receptor activity	Molecular Function	IDA[12218053]	36
GO:0005515	protein binding	Molecular Function	IPI[19377461]	910
GO:0006356	regulation of transcription from RNA polymerase I promoter	Biological Process	IDA[16314496]	1
GO:0006367	transcription initiation from RNA polymerase II promoter	Biological Process	IDA[12218053]	42
GO:0005730	nucleolus	Cellular Component	IDA[16314496]	243
GO:0006260	DNA replication	Biological Process		27
GO:0007420	brain development	Biological Process		33
GO:0007595	lactation	Biological Process		7
GO:0006590	thyroid hormone generation	Biological Process		5
GO:0006702	androgen biosynthetic process	Biological Process	IMP[19497978]	4
GO:0000981	sequence-specific DNA binding RNA polymerase II transcription factor activity	Molecular Function		6
GO:0000902	cell morphogenesis	Biological Process	IMP[17223341]	7
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	Biological Process		78
GO:0001889	liver development	Biological Process		14
GO:0001525	angiogenesis	Biological Process		35
GO:0001104	RNA polymerase II transcription cofactor activity	Molecular Function	IDA[10198638]	16
GO:0001047	core promoter binding	Molecular Function	IDA[17641689]	2
GO:0003222	ventricular trabecula myocardium morphogenesis	Biological Process		3
GO:0002154	thyroid hormone mediated signaling pathway	Biological Process	IMP[16314496]	1
GO:0002088	lens development in camera-type eye	Biological Process		7
GO:0001892	embryonic placenta development	Biological Process		4

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MED1 (count: 132)

Gene Symbol	Pathway Count	Pathway List
MED12	18	thyroid hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; gene expression; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription cofactor activity; transcription coactivator activity; chromatin binding; nucleus; nucleoplasm; receptor activity; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcription cofactor activity;
MED13	17	thyroid hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; gene expression; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription cofactor activity; transcription coactivator activity; nucleus; nucleoplasm; receptor activity; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcription cofactor activity;
MED14	17	thyroid hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; gene expression; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription cofactor activity; transcription coactivator activity; nucleus; nucleoplasm; receptor activity; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcription cofactor activity;
MED17	17	thyroid hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; gene expression; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription cofactor activity; transcription coactivator activity; nucleus; nucleoplasm; receptor activity; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcription cofactor activity;
MED4	17	thyroid hormone receptor binding; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; gene expression; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription cofactor activity; nucleus; nucleoplasm; receptor activity; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus; RNA polymerase II transcription cofactor activity;
NCOA6	17	thyroid hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; cellular lipid metabolic process; small molecule metabolic process; ligand-dependent nuclear receptor transcription coactivator activity; estrogen receptor binding; transcription coactivator activity; chromatin binding; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus; DNA replication; brain development;
THRAP3	17	thyroid hormone receptor binding; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription cofactor activity; transcription coactivator activity; nucleus; receptor activity; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus; RNA polymerase II transcription cofactor activity;
MED30	16	thyroid hormone receptor binding; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; gene expression; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription cofactor activity; nucleus; nucleoplasm; receptor activity; protein binding; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcription cofactor activity;
MED16	15	thyroid hormone receptor binding; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; gene expression; mediator complex; intracellular steroid hormone receptor signaling pathway; thyroid hormone receptor coactivator activity; androgen receptor signaling pathway; transcription cofactor activity; transcription coactivator activity; nucleus; nucleoplasm; receptor activity; transcription initiation from RNA polymerase II promoter;
MED24	15	thyroid hormone receptor binding; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; vitamin D receptor binding; gene expression; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; intracellular steroid hormone receptor signaling pathway; androgen receptor signaling pathway; transcription cofactor activity; nucleus; nucleoplasm; receptor activity; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcription cofactor activity;
SNW1	13	regulation of vitamin D receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; nuclear hormone receptor binding; vitamin D receptor binding; retinoic acid receptor binding; gene expression; transcription coactivator activity; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
TFAP2A	11	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; positive regulation of gene expression; transcription coactivator activity; chromatin binding; nucleus; protein binding; nucleolus; sequence-specific DNA binding RNA polymerase II transcription factor activity; negative regulation of transcription from RNA polymerase II promoter;
SMARCD3	11	positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; cellular lipid metabolic process; small molecule metabolic process; transcription factor binding; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; transcription coactivator activity; nucleus; nucleoplasm; protein binding;
NCOR1	10	thyroid hormone receptor binding; cellular lipid metabolic process; small molecule metabolic process; gene expression; chromatin binding; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter;
NSD1	10	thyroid hormone receptor binding; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; retinoic acid receptor binding; ligand-dependent nuclear receptor binding; estrogen receptor binding; transcription cofactor activity; chromatin binding; nucleus; negative regulation of transcription from RNA polymerase II promoter;
GATA6	10	positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; transcription factor binding; chromatin binding; nucleus; nucleoplasm; protein binding; sequence-specific DNA binding RNA polymerase II transcription factor activity; negative regulation of transcription from RNA polymerase II promoter; liver development;
MEN1	10	positive regulation of transcription from RNA polymerase II promoter; gene expression; chromatin binding; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus; brain development; negative regulation of transcription from RNA polymerase II promoter;
RBPJ	10	positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus; negative regulation of transcription from RNA polymerase II promoter; angiogenesis; ventricular trabecula myocardium morphogenesis;
YAP1	10	positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; gene expression; keratinocyte differentiation; transcription coactivator activity; chromatin binding; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter;
NCOR2	10	cellular lipid metabolic process; small molecule metabolic process; gene expression; chromatin binding; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
KDM1A	9	positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; transcription factor binding; ligand-dependent nuclear receptor transcription coactivator activity; chromatin binding; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter;
NRIP1	9	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; estrogen receptor binding; androgen receptor signaling pathway; transcription coactivator activity; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter;
RELA	9	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; transcription factor binding; chromatin binding; nucleus; nucleoplasm; protein binding; liver development;
HMGA1	9	positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; retinoic acid receptor binding; peroxisome proliferator activated receptor binding; transcription factor binding; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; nucleoplasm; protein binding;
PPARGC1B	8	positive regulation of receptor activity; positive regulation of transcription from RNA polymerase II promoter; nuclear hormone receptor binding; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; estrogen receptor binding; nucleus; RNA polymerase II transcription cofactor activity;
KAT5	8	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; androgen receptor signaling pathway; transcription coactivator activity; nucleus; protein binding; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
LPIN1	8	positive regulation of transcription from RNA polymerase II promoter; peroxisome proliferator activated receptor binding; cellular lipid metabolic process; small molecule metabolic process; organ regeneration; transcription coactivator activity; nucleus; negative regulation of transcription from RNA polymerase II promoter;
MAML1	8	positive regulation of transcription from RNA polymerase II promoter; gene expression; transcription coactivator activity; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus;
NR5A1	8	positive regulation of transcription from RNA polymerase II promoter; gene expression; transcription coactivator activity; chromatin binding; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter;
RBM14	8	positive regulation of transcription from RNA polymerase II promoter; mediator complex; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; protein binding; nucleolus; DNA replication; RNA polymerase II transcription cofactor activity;
VEGFA	8	positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; positive regulation of gene expression; monocyte differentiation; protein binding; lactation; negative regulation of transcription from RNA polymerase II promoter; angiogenesis;
HINFP	8	positive regulation of transcription, DNA-dependent; positive regulation of gene expression; transcription coactivator activity; chromatin binding; nucleus; nucleoplasm; protein binding; nucleolus;
CCND1	8	fat cell differentiation; positive regulation of mammary gland epithelial cell proliferation; organ regeneration; nucleus; nucleoplasm; protein binding; lactation; liver development;
CTGF	8	positive regulation of G0 to G1 transition; cellular lipid metabolic process; small molecule metabolic process; gene expression; positive regulation of gene expression; transcription initiation from RNA polymerase II promoter; DNA replication; angiogenesis;
NUP62	7	thyroid hormone receptor binding; positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; negative regulation of apoptotic process; small molecule metabolic process; chromatin binding; protein binding;
FOXC2	7	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; embryonic heart tube development; negative regulation of apoptotic process; transcription factor binding; nucleus; negative regulation of transcription from RNA polymerase II promoter;
HNF1B	7	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; nucleus; protein binding; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
ISL1	7	positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron differentiation; ligand-dependent nuclear receptor binding; estrogen receptor binding; chromatin binding; nucleus; negative regulation of transcription from RNA polymerase II promoter;
PRPF6	7	positive regulation of transcription from RNA polymerase II promoter; nuclear hormone receptor binding; gene expression; transcription coactivator activity; nucleus; nucleoplasm; protein binding;
ID2	7	positive regulation of transcription, DNA-dependent; negative regulation of neuron differentiation; positive regulation of gene expression; nucleus; protein binding; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
MAPK1	7	positive regulation of transcription, DNA-dependent; ERK1 and ERK2 cascade; transcription factor binding; nucleus; nucleoplasm; protein binding; nucleolus;
RAN	7	positive regulation of transcription, DNA-dependent; gene expression; androgen receptor signaling pathway; transcription coactivator activity; chromatin binding; nucleoplasm; protein binding;
NIPBL	7	fat cell differentiation; mediator complex binding; chromatin binding; nucleus; protein binding; brain development; negative regulation of transcription from RNA polymerase II promoter;
SMC1A	7	mediator complex binding; gene expression; chromatin binding; nucleus; nucleoplasm; protein binding; nucleolus;
MED15	7	gene expression; mediator complex; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcription cofactor activity;
MED7	7	gene expression; mediator complex; transcription coactivator activity; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; RNA polymerase II transcription cofactor activity;
SSRP1	7	gene expression; chromatin binding; nucleus; nucleoplasm; protein binding; nucleolus; DNA replication;
TAF10	7	gene expression; estrogen receptor binding; transcription coactivator activity; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter;
E2F5	6	positive regulation of transcription from RNA polymerase II promoter; gene expression; transcription factor binding; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter;
ESRRA	6	positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter;
FGF10	6	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; ERK1 and ERK2 cascade; negative regulation of apoptotic process; nucleus; angiogenesis;
FOXE1	6	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription factor binding; nucleus; thyroid hormone generation; negative regulation of transcription from RNA polymerase II promoter;
FOXG1	6	positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron differentiation; transcription factor binding; nucleus; protein binding; brain development;
GSK3B	6	positive regulation of transcription from RNA polymerase II promoter; fat cell differentiation; negative regulation of apoptotic process; nucleus; protein binding; nucleolus;
HES1	6	positive regulation of transcription from RNA polymerase II promoter; transcription factor binding; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; liver development;
HEY2	6	positive regulation of transcription from RNA polymerase II promoter; transcription factor binding; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter; ventricular trabecula myocardium morphogenesis;
IRF7	6	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter;
MAML2	6	positive regulation of transcription from RNA polymerase II promoter; gene expression; transcription coactivator activity; nucleus; nucleoplasm; transcription initiation from RNA polymerase II promoter;
MAPK3	6	positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
MEIS2	6	positive regulation of transcription from RNA polymerase II promoter; transcription factor binding; transcription cofactor activity; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter;
MTA2	6	positive regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleus; protein binding; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
NR4A2	6	positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter;
SMARCB1	6	positive regulation of transcription from RNA polymerase II promoter; transcription coactivator activity; nucleus; nucleoplasm; protein binding; nucleolus;
TP53BP1	6	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; nucleus; nucleoplasm; protein binding; RNA polymerase II transcription cofactor activity;
UBB	6	positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter;
UBC	6	positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter;
UBE3A	6	positive regulation of transcription from RNA polymerase II promoter; androgen receptor signaling pathway; transcription coactivator activity; nucleus; protein binding; brain development;
APBB1	6	positive regulation of transcription, DNA-dependent; negative regulation of neuron differentiation; transcription factor binding; chromatin binding; nucleus; protein binding;
MMS19	6	positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; estrogen receptor binding; transcription coactivator activity; nucleus; protein binding;
RNF20	6	positive regulation of transcription, DNA-dependent; transcription coactivator activity; chromatin binding; nucleus; protein binding; nucleolus;
PLK1	6	regulation of cell cycle; negative regulation of apoptotic process; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter;
DAXX	6	nuclear hormone receptor binding; transcription factor binding; androgen receptor signaling pathway; nucleus; protein binding; nucleolus;
PSMC3	6	small molecule metabolic process; gene expression; transcription coactivator activity; nucleus; nucleoplasm; protein binding;
MED23	6	gene expression; mediator complex; transcription coactivator activity; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter;
NEDD4L	6	gene expression; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter;
PGR	6	gene expression; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus;
TAF13	6	gene expression; nucleus; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter; nucleolus;
TRIP12	5	thyroid hormone receptor binding; nuclear hormone receptor binding; nucleus; nucleoplasm; protein binding;
AATF	5	positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; nucleus; protein binding; nucleolus;
ATXN1	5	positive regulation of transcription from RNA polymerase II promoter; nucleus; nucleoplasm; protein binding; nucleolus;
CBFA2T3	5	positive regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleoplasm; protein binding; nucleolus;
ETS1	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription factor binding; nucleus; protein binding;
FLCN	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of gene expression; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter;
FOXF1	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; transcription factor binding; nucleus; negative regulation of transcription from RNA polymerase II promoter;
FOXP1	5	positive regulation of transcription from RNA polymerase II promoter; transcription factor binding; chromatin binding; nucleus; nucleolus;
HOXA2	5	positive regulation of transcription from RNA polymerase II promoter; negative regulation of neuron differentiation; nucleus; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
HOXA7	5	positive regulation of transcription from RNA polymerase II promoter; transcription factor binding; nucleus; negative regulation of transcription from RNA polymerase II promoter; angiogenesis;
MAPK7	5	positive regulation of transcription from RNA polymerase II promoter; negative regulation of apoptotic process; nucleus; nucleoplasm; protein binding;
MLL	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; embryonic hemopoiesis; nucleus; protein binding;
MYB	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; chromatin binding; protein binding; negative regulation of transcription from RNA polymerase II promoter;
NCOA7	5	positive regulation of transcription from RNA polymerase II promoter; nuclear hormone receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; protein binding;
POU2F3	5	positive regulation of transcription from RNA polymerase II promoter; keratinocyte differentiation; nucleus; protein binding; nucleolus;
PRKD1	5	positive regulation of transcription from RNA polymerase II promoter; small molecule metabolic process; nucleus; protein binding; angiogenesis;
RORA	5	positive regulation of transcription from RNA polymerase II promoter; gene expression; nucleoplasm; protein binding; transcription initiation from RNA polymerase II promoter;
SPI1	5	positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; protein binding; negative regulation of transcription from RNA polymerase II promoter; core promoter binding;
SREBF1	5	positive regulation of transcription from RNA polymerase II promoter; chromatin binding; nucleus; protein binding; negative regulation of transcription from RNA polymerase II promoter;
SS18	5	positive regulation of transcription from RNA polymerase II promoter; ligand-dependent nuclear receptor transcription coactivator activity; nucleus; protein binding; cell morphogenesis;
STRN3	5	positive regulation of transcription from RNA polymerase II promoter; nucleus; nucleoplasm; protein binding; negative regulation of transcription from RNA polymerase II promoter;
MAPK9	5	positive regulation of transcription, DNA-dependent; transcription factor binding; positive regulation of gene expression; nucleoplasm; protein binding;
RRN3	5	positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; gene expression; nucleoplasm; nucleolus;
TGFB1I1	5	positive regulation of transcription, DNA-dependent; nuclear hormone receptor binding; androgen receptor signaling pathway; transcription coactivator activity; protein binding;
TGFBR1	5	positive regulation of transcription, DNA-dependent; negative regulation of apoptotic process; protein binding; angiogenesis; lens development in camera-type eye;
TRIM32	5	fat cell differentiation; negative regulation of apoptotic process; transcription coactivator activity; nucleus; protein binding;
BIRC2	5	regulation of cell cycle; negative regulation of apoptotic process; transcription coactivator activity; nucleus; protein binding;
HSPA8	5	regulation of cell cycle; gene expression; nucleus; protein binding; nucleolus;
ZFPM1	5	embryonic hemopoiesis; megakaryocyte development; transcription factor binding; nucleoplasm; protein binding;
SMC3	5	mediator complex binding; chromatin binding; nucleus; nucleoplasm; protein binding;
PRKAA1	5	negative regulation of apoptotic process; positive regulation of gene expression; chromatin binding; nucleus; protein binding;
XRCC5	5	negative regulation of apoptotic process; nucleus; nucleoplasm; protein binding; nucleolus;
APOA1	5	cellular lipid metabolic process; small molecule metabolic process; organ regeneration; nucleus; protein binding;
DDX23	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
DGCR8	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
DHX9	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
EFTUD2	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
FUS	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
HNRNPA2B1	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
HNRNPH1	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
NR4A3	5	gene expression; organ regeneration; nucleus; nucleoplasm; transcription initiation from RNA polymerase II promoter;
PRPF4	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
SF3A1	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
SF3A3	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
SNRNP200	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
TAF4B	5	gene expression; nucleus; nucleoplasm; transcription initiation from RNA polymerase II promoter; nucleolus;
U2AF1	5	gene expression; nucleus; nucleoplasm; protein binding; nucleolus;
XPO1	5	gene expression; nucleoplasm; protein binding; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
AIP	5	transcription factor binding; transcription coactivator activity; nucleus; protein binding; nucleolus;
PHF2	5	transcription coactivator activity; nucleus; protein binding; nucleolus; liver development;
RCC1	5	chromatin binding; nucleus; nucleoplasm; protein binding; nucleolus;
RNF2	5	chromatin binding; nucleus; protein binding; nucleolus; negative regulation of transcription from RNA polymerase II promoter;
FEN1	5	nucleus; nucleoplasm; protein binding; nucleolus; DNA replication;
RAD1	5	nucleus; nucleoplasm; protein binding; nucleolus; DNA replication;
RAD9A	5	nucleus; nucleoplasm; protein binding; nucleolus; DNA replication;

Genes shared at least 2 KEGG pathways with MED1 (count: 0)

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Region: chr17:37560538..37607527 View in gBrowse