ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MMP10
Previous Symbol	STMY2
Approved Name	matrix metallopeptidase 10 (stromelysin 2)
Previous Name	matrix metalloproteinase 10 (stromelysin 2)
Location	11q22.3
Position	chr11:102641233-102651359, -
External Links	HGNC: 7156 Entrez Gene: 4319 Ensembl: ENSG00000166670 UCSC: uc001phg.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)
11q22	chr11:97200000-110400000	1 (1/0/0)

Gene related GO terms (count: 11)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005615	extracellular space	Cellular Component	TAS[2844164]	126
GO:0006508	proteolysis	Biological Process		102
GO:0008270	zinc ion binding	Molecular Function		323
GO:0022617	extracellular matrix disassembly	Biological Process		14
GO:0004222	metalloendopeptidase activity	Molecular Function		33
GO:0005509	calcium ion binding	Molecular Function		124
GO:0005576	extracellular region	Cellular Component		240
GO:0005578	proteinaceous extracellular matrix	Cellular Component		47
GO:0030574	collagen catabolic process	Biological Process		10
GO:0030334	regulation of cell migration	Biological Process		10
GO:0030198	extracellular matrix organization	Biological Process		31

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MMP10 (count: 17)

Gene Symbol	Pathway Count	Pathway List
MMP3	11	extracellular space; proteolysis; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding; extracellular region; proteinaceous extracellular matrix; collagen catabolic process; regulation of cell migration; extracellular matrix organization;
MMP13	10	extracellular space; proteolysis; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding; extracellular region; proteinaceous extracellular matrix; collagen catabolic process; extracellular matrix organization;
MMP8	10	extracellular space; proteolysis; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding; extracellular region; proteinaceous extracellular matrix; collagen catabolic process; extracellular matrix organization;
MMP7	9	extracellular space; proteolysis; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; extracellular region; proteinaceous extracellular matrix; collagen catabolic process; extracellular matrix organization;
MMP1	9	proteolysis; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding; extracellular region; proteinaceous extracellular matrix; collagen catabolic process; extracellular matrix organization;
MMP11	9	proteolysis; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding; extracellular region; proteinaceous extracellular matrix; collagen catabolic process; extracellular matrix organization;
MMP16	8	proteolysis; zinc ion binding; extracellular matrix disassembly; metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; collagen catabolic process; extracellular matrix organization;
ADAMTS2	7	proteolysis; zinc ion binding; metalloendopeptidase activity; extracellular region; proteinaceous extracellular matrix; collagen catabolic process; extracellular matrix organization;
MMP20	6	extracellular space; proteolysis; zinc ion binding; metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix;
MMP27	6	proteolysis; zinc ion binding; metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix; collagen catabolic process;
TLL1	6	proteolysis; zinc ion binding; metalloendopeptidase activity; calcium ion binding; extracellular region; extracellular matrix organization;
CTRB1	5	extracellular space; proteolysis; extracellular matrix disassembly; extracellular region; extracellular matrix organization;
CTRB2	5	extracellular space; proteolysis; extracellular matrix disassembly; extracellular region; extracellular matrix organization;
CTSG	5	extracellular space; proteolysis; extracellular matrix disassembly; extracellular region; extracellular matrix organization;
MMP12	5	proteolysis; zinc ion binding; metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix;
MMP24	5	proteolysis; zinc ion binding; metalloendopeptidase activity; calcium ion binding; proteinaceous extracellular matrix;
TLL2	5	proteolysis; zinc ion binding; metalloendopeptidase activity; calcium ion binding; extracellular region;

Genes shared at least 2 KEGG pathways with MMP10 (count: 0)

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Region: chr11:102641233..102651359 View in gBrowse