ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	MYO7A
Previous Symbol	USH1B, DFNB2, DFNA11
Symbol Alias	NSRD2
Approved Name	myosin VIIA
Previous Name	myosin VIIA (Usher syndrome 1B (autosomal recessive, severe))
Location	11q13.5
Position	chr11:76839310-76926286, +
External Links	HGNC: 7606 Entrez Gene: 4647 Ensembl: ENSG00000137474 UCSC: uc001oyb.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 30)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 30)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0050953	sensory perception of light stimulus	Biological Process	IMP[11398101]	3
GO:0048563	post-embryonic organ morphogenesis	Biological Process		1
GO:0051015	actin filament binding	Molecular Function		14
GO:0050957	equilibrioception	Biological Process	IMP[7870171]	2
GO:0060088	auditory receptor cell stereocilium organization	Biological Process		2
GO:0051904	pigment granule transport	Biological Process		1
GO:0030048	actin filament-based movement	Biological Process		1
GO:0019904	protein domain specific binding	Molecular Function		40
GO:0032420	stereocilium	Cellular Component		6
GO:0032391	photoreceptor connecting cilium	Cellular Component		2
GO:0042470	melanosome	Cellular Component		22
GO:0042462	eye photoreceptor cell development	Biological Process	IC[8842737]	3
GO:0046983	protein dimerization activity	Molecular Function	RCA[8622919]	26
GO:0045202	synapse	Cellular Component	IDA[8842737]	31
GO:0005829	cytosol	Cellular Component	IDA[15300860]	447
GO:0005938	cell cortex	Cellular Component		26
GO:0006886	intracellular protein transport	Biological Process		43
GO:0007040	lysosome organization	Biological Process	IDA[16001398]	7
GO:0007601	visual perception	Biological Process	IMP[7870171]	30
GO:0007605	sensory perception of sound	Biological Process	IMP[11398101]	31
GO:0016324	apical plasma membrane	Cellular Component		51
GO:0016459	myosin complex	Cellular Component		4
GO:0000146	microfilament motor activity	Molecular Function		2
GO:0001750	photoreceptor outer segment	Cellular Component	IDA[8842737]	8
GO:0001845	phagolysosome assembly	Biological Process		2
GO:0001917	photoreceptor inner segment	Cellular Component	IDA[8842737]	5
GO:0005515	protein binding	Molecular Function		910
GO:0005516	calmodulin binding	Molecular Function	IMP[15300860]	32
GO:0005524	ATP binding	Molecular Function		228
GO:0005765	lysosomal membrane	Cellular Component	IDA[16001398]	17

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with MYO7A (count: 6)

Gene Symbol	Pathway Count	Pathway List
TH	6	protein domain specific binding; eye photoreceptor cell development; cytosol; visual perception; sensory perception of sound; protein binding;
CDH23	5	sensory perception of light stimulus; equilibrioception; stereocilium; sensory perception of sound; protein binding;
RAB27A	5	protein domain specific binding; melanosome; apical plasma membrane; photoreceptor outer segment; protein binding;
MYO15A	5	stereocilium; sensory perception of sound; myosin complex; calmodulin binding; ATP binding;
MYH11	5	melanosome; cytosol; protein binding; calmodulin binding; ATP binding;
MYO5B	5	myosin complex; microfilament motor activity; protein binding; calmodulin binding; ATP binding;

Genes shared at least 2 KEGG pathways with MYO7A (count: 0)

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Region: chr11:76839310..76926286 View in gBrowse