ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NMNAT3
Symbol Alias	PNAT3
Approved Name	nicotinamide nucleotide adenylyltransferase 3
Location	3q23
Position	chr3:139279022-139396859, -
External Links	HGNC: 20989 Entrez Gene: 349565 Ensembl: ENSG00000163864 UCSC: uc003etk.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Jarick[2012]_8	chr3:140757013-141415656 (NCBI36 / hg18)	658644	3q23	dup

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005829	cytosol	Cellular Component		447
GO:0005739	mitochondrion	Cellular Component	IDA[16118205]	183
GO:0005524	ATP binding	Molecular Function		228
GO:0004515	nicotinate-nucleotide adenylyltransferase activity	Molecular Function	IDA[16118205]	2
GO:0000309	nicotinamide-nucleotide adenylyltransferase activity	Molecular Function		2
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0019674	NAD metabolic process	Biological Process		5
GO:0009611	response to wounding	Biological Process		9
GO:0009435	NAD biosynthetic process	Biological Process	IC[16118205]	6
GO:0006767	water-soluble vitamin metabolic process	Biological Process		13
GO:0006766	vitamin metabolic process	Biological Process		13

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00760	Nicotinate and nicotinamide metabolism	9

Genes shared at least 5 GO terms with NMNAT3 (count: 5)

Gene Symbol	Pathway Count	Pathway List
NMNAT2	8	ATP binding; nicotinate-nucleotide adenylyltransferase activity; nicotinamide-nucleotide adenylyltransferase activity; small molecule metabolic process; NAD metabolic process; NAD biosynthetic process; water-soluble vitamin metabolic process; vitamin metabolic process;
NADSYN1	7	cytosol; ATP binding; small molecule metabolic process; NAD metabolic process; NAD biosynthetic process; water-soluble vitamin metabolic process; vitamin metabolic process;
NAPRT1	6	cytosol; small molecule metabolic process; NAD metabolic process; NAD biosynthetic process; water-soluble vitamin metabolic process; vitamin metabolic process;
QPRT	6	cytosol; small molecule metabolic process; NAD metabolic process; NAD biosynthetic process; water-soluble vitamin metabolic process; vitamin metabolic process;
SHMT1	5	cytosol; mitochondrion; small molecule metabolic process; water-soluble vitamin metabolic process; vitamin metabolic process;

Genes shared at least 2 KEGG pathways with NMNAT3 (count: 8)

Gene Symbol	Pathway Count	Pathway List
ENPP1	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
ENPP3	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NADSYN1	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NAPRT1	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NMNAT2	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NNMT	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NT5M	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
QPRT	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;

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Region: chr3:139279022..139396859 View in gBrowse