ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NT5M
Symbol Alias	dNT-2, dNT2, mdN
Approved Name	5',3'-nucleotidase, mitochondrial
Previous Name	5' nucleotidase, mitochondrial
Location	17p11.2
Position	chr17:17206649-17250977, +
External Links	HGNC: 15769 Entrez Gene: 56953 Ensembl: ENSG00000205309 UCSC: uc002grf.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
17p11	chr17:16000000-24000000	3 (2/0/1)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0046079	dUMP catabolic process	Biological Process		1
GO:0046135	pyrimidine nucleoside catabolic process	Biological Process		3
GO:0046872	metal ion binding	Molecular Function		170
GO:0055086	nucleobase-containing small molecule metabolic process	Biological Process		9
GO:0008253	5'-nucleotidase activity	Molecular Function		1
GO:0009223	pyrimidine deoxyribonucleotide catabolic process	Biological Process	TAS[10899995]	1
GO:0006260	DNA replication	Biological Process	TAS[10899995]	27
GO:0008252	nucleotidase activity	Molecular Function	TAS[10899995]	1
GO:0005759	mitochondrial matrix	Cellular Component		32
GO:0006206	pyrimidine nucleobase metabolic process	Biological Process		3
GO:0000166	nucleotide binding	Molecular Function		73
GO:0005739	mitochondrion	Cellular Component	TAS[10899995]	183

Gene related KEGG pathways (count: 4)

ID	Name	No. of Genes in ADHDgene
hsa00230	Purine metabolism	22
hsa01100	Metabolic pathways	237
hsa00240	Pyrimidine metabolism	13
hsa00760	Nicotinate and nicotinamide metabolism	9

Genes shared at least 5 GO terms with NT5M (count: 2)

Gene Symbol	Pathway Count	Pathway List
AGXT2	6	small molecule metabolic process; pyrimidine nucleoside catabolic process; nucleobase-containing small molecule metabolic process; mitochondrial matrix; pyrimidine nucleobase metabolic process; mitochondrion;
UPB1	5	small molecule metabolic process; pyrimidine nucleoside catabolic process; metal ion binding; nucleobase-containing small molecule metabolic process; pyrimidine nucleobase metabolic process;

Genes shared at least 2 KEGG pathways with NT5M (count: 21)

Gene Symbol	Pathway Count	Pathway List
ENPP1	3	Purine metabolism; Metabolic pathways; Nicotinate and nicotinamide metabolism;
ENPP3	3	Purine metabolism; Metabolic pathways; Nicotinate and nicotinamide metabolism;
ITPA	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
POLA2	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
POLD3	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
POLD4	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
POLE	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
POLE3	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
POLR1A	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
POLR2G	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
RRM2	3	Purine metabolism; Metabolic pathways; Pyrimidine metabolism;
APRT	2	Purine metabolism; Metabolic pathways;
ATIC	2	Purine metabolism; Metabolic pathways;
POLR3E	2	Purine metabolism; Pyrimidine metabolism;
NADSYN1	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NAPRT1	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NMNAT2	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NMNAT3	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
NNMT	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
QPRT	2	Metabolic pathways; Nicotinate and nicotinamide metabolism;
UPB1	2	Metabolic pathways; Pyrimidine metabolism;

View in gBrowse

Region: chr17:17206649..17250977 View in gBrowse