ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SERPINH1
Previous Symbol	CBP1, CBP2, SERPINH2
Symbol Alias	HSP47, colligen
Approved Name	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
Previous Name	serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, "serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)"
Location	11q13.5
Position	chr11:75273101-75283846, +
External Links	HGNC: 1546 Entrez Gene: 871 Ensembl: ENSG00000149257 UCSC: uc001owr.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006986	response to unfolded protein	Biological Process	TAS[1309665]	10
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	Cellular Component	IDA[15308636]	17
GO:0005788	endoplasmic reticulum lumen	Cellular Component		33
GO:0005783	endoplasmic reticulum	Cellular Component	NAS[7656593]	100
GO:0005518	collagen binding	Molecular Function	NAS[7656593]	8
GO:0004867	serine-type endopeptidase inhibitor activity	Molecular Function		10
GO:0051604	protein maturation	Biological Process		1
GO:0051082	unfolded protein binding	Molecular Function		19
GO:0032964	collagen biosynthetic process	Biological Process		2
GO:0030199	collagen fibril organization	Biological Process		5
GO:0030198	extracellular matrix organization	Biological Process		31
GO:0030162	regulation of proteolysis	Biological Process		6
GO:0010951	negative regulation of endopeptidase activity	Biological Process		7

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with SERPINH1 (count: 0)

Genes shared at least 2 KEGG pathways with SERPINH1 (count: 0)

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Region: chr11:75273101..75283846 View in gBrowse