ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TAX1BP1
Symbol Alias	TXBP151, CALCOCO3
Approved Name	Tax1 (human T-cell leukemia virus type I) binding protein 1
Location	7p15
Position	chr7:27778950-27880938, +
External Links	HGNC: 11575 Entrez Gene: 8887 Ensembl: ENSG00000106052 UCSC: uc003szl.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
7p15	chr7:20900000-28800000	2 (1/1/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005515	protein binding	Molecular Function	IPI[15474016]	910
GO:0032088	negative regulation of NF-kappaB transcription factor activity	Biological Process		10
GO:0032480	negative regulation of type I interferon production	Biological Process		10
GO:0043066	negative regulation of apoptotic process	Biological Process		77
GO:0045087	innate immune response	Biological Process		54
GO:0005829	cytosol	Cellular Component		447
GO:0006915	apoptotic process	Biological Process		111
GO:0008270	zinc ion binding	Molecular Function		323
GO:0019900	kinase binding	Molecular Function		7

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TAX1BP1 (count: 7)

Gene Symbol	Pathway Count	Pathway List
TNFAIP3	8	protein binding; negative regulation of NF-kappaB transcription factor activity; negative regulation of type I interferon production; negative regulation of apoptotic process; innate immune response; cytosol; zinc ion binding; kinase binding;
ARHGEF2	5	protein binding; negative regulation of apoptotic process; cytosol; apoptotic process; zinc ion binding;
ATG5	5	protein binding; negative regulation of type I interferon production; negative regulation of apoptotic process; innate immune response; apoptotic process;
BIRC2	5	protein binding; negative regulation of apoptotic process; cytosol; apoptotic process; zinc ion binding;
MAPK7	5	protein binding; negative regulation of apoptotic process; innate immune response; cytosol; apoptotic process;
UBB	5	protein binding; negative regulation of type I interferon production; innate immune response; cytosol; apoptotic process;
UBC	5	protein binding; negative regulation of type I interferon production; innate immune response; cytosol; apoptotic process;

Genes shared at least 2 KEGG pathways with TAX1BP1 (count: 0)

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Region: chr7:27778950..27880938 View in gBrowse