ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	TMED10
Symbol Alias	TMP21, P24(DELTA)
Approved Name	transmembrane emp24-like trafficking protein 10 (yeast)
Location	14q24.3
Position	chr14:75598171-75643349, -
External Links	HGNC: 16998 Entrez Gene: 10972 Ensembl: ENSG00000170348 UCSC: uc001xrm.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 33)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048193	Golgi vesicle transport	Biological Process		49

GO terms by database search (count: 32)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001101	response to acid	Biological Process		1
GO:0001822	kidney development	Biological Process		16
GO:0005515	protein binding	Molecular Function		910
GO:0005783	endoplasmic reticulum	Cellular Component	IDA[12237308]	100
GO:0005789	endoplasmic reticulum membrane	Cellular Component		140
GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	Cellular Component	IDA[12237308]	17
GO:0005794	Golgi apparatus	Cellular Component	IDA[12237308]	157
GO:0005801	cis-Golgi network	Cellular Component		14
GO:0030667	secretory granule membrane	Cellular Component		5
GO:0030658	transport vesicle membrane	Cellular Component		4
GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane	Cellular Component		10
GO:0032403	protein complex binding	Molecular Function		27
GO:0035459	cargo loading into vesicle	Biological Process		2
GO:0034205	beta-amyloid formation	Biological Process	IMP[16641999]	1
GO:0042470	melanosome	Cellular Component		22
GO:0035964	COPI-coated vesicle budding	Biological Process	IDA[10052452]	1
GO:0006886	intracellular protein transport	Biological Process		43
GO:0005886	plasma membrane	Cellular Component		772
GO:0006890	retrograde vesicle-mediated transport, Golgi to ER	Biological Process		16
GO:0006888	ER to Golgi vesicle-mediated transport	Biological Process		24
GO:0016021	integral to membrane	Cellular Component		845
GO:0007030	Golgi organization	Biological Process		11
GO:0030140	trans-Golgi network transport vesicle	Cellular Component		7
GO:0030137	COPI-coated vesicle	Cellular Component		4
GO:0070765	gamma-secretase complex	Cellular Component	IDA[16641999]	1
GO:0045055	regulated secretory pathway	Biological Process		2
GO:0042589	zymogen granule membrane	Cellular Component		4
GO:0043279	response to alkaloid	Biological Process		1
GO:0048208	COPII vesicle coating	Biological Process		2
GO:0051259	protein oligomerization	Biological Process		8
GO:0048199	vesicle targeting, to, from or within Golgi	Biological Process		1
GO:0048205	COPI coating of Golgi vesicle	Biological Process	TAS[10761932]	8

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TMED10 (count: 39)

Gene Symbol	Pathway Count	Pathway List
TMED2	15	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment membrane; cargo loading into vesicle; intracellular protein transport; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi organization; COPI-coated vesicle; zymogen granule membrane; COPII vesicle coating; COPI coating of Golgi vesicle;
COG3	8	protein binding; Golgi apparatus; cis-Golgi network; intracellular protein transport; plasma membrane; retrograde vesicle-mediated transport, Golgi to ER; ER to Golgi vesicle-mediated transport; Golgi vesicle transport;
LMAN1	8	protein binding; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi organization; Golgi vesicle transport;
SEC22B	8	protein binding; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; melanosome; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi vesicle transport;
COPB1	7	protein binding; endoplasmic reticulum-Golgi intermediate compartment; intracellular protein transport; plasma membrane; retrograde vesicle-mediated transport, Golgi to ER; Golgi vesicle transport; COPI coating of Golgi vesicle;
ERGIC1	7	protein binding; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; endoplasmic reticulum-Golgi intermediate compartment membrane; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi vesicle transport;
STX18	7	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; intracellular protein transport; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi vesicle transport;
BET1	6	protein binding; endoplasmic reticulum membrane; cis-Golgi network; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi vesicle transport;
PDIA6	6	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; melanosome; plasma membrane;
STX6	6	protein binding; Golgi apparatus; intracellular protein transport; plasma membrane; integral to membrane; Golgi vesicle transport;
USE1	6	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi vesicle transport;
STX5	6	endoplasmic reticulum; Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment membrane; intracellular protein transport; ER to Golgi vesicle-mediated transport; integral to membrane;
ATP10A	5	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; plasma membrane; integral to membrane;
COG7	5	protein binding; Golgi apparatus; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER; Golgi vesicle transport;
GJA1	5	protein binding; endoplasmic reticulum membrane; Golgi apparatus; plasma membrane; protein oligomerization;
GOPC	5	protein binding; Golgi apparatus; plasma membrane; ER to Golgi vesicle-mediated transport; trans-Golgi network transport vesicle;
HSPA5	5	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; melanosome;
PRKD1	5	protein binding; Golgi apparatus; plasma membrane; Golgi organization; Golgi vesicle transport;
PTCH1	5	protein binding; Golgi apparatus; protein complex binding; plasma membrane; integral to membrane;
SREBF1	5	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; protein complex binding; integral to membrane;
STIM2	5	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; plasma membrane; integral to membrane;
STX16	5	protein binding; Golgi apparatus; intracellular protein transport; integral to membrane; Golgi vesicle transport;
SYTL2	5	protein binding; Golgi apparatus; melanosome; intracellular protein transport; plasma membrane;
TAPBP	5	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; retrograde vesicle-mediated transport, Golgi to ER; integral to membrane;
YIF1A	5	protein binding; endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment; Golgi apparatus; integral to membrane;
ZW10	5	protein binding; endoplasmic reticulum; endoplasmic reticulum membrane; ER to Golgi vesicle-mediated transport; Golgi vesicle transport;
ATL3	5	endoplasmic reticulum; endoplasmic reticulum membrane; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi organization;
SEC22C	5	endoplasmic reticulum; endoplasmic reticulum membrane; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi vesicle transport;
STS	5	endoplasmic reticulum; endoplasmic reticulum membrane; Golgi apparatus; plasma membrane; integral to membrane;
ZP2	5	endoplasmic reticulum; Golgi apparatus; intracellular protein transport; plasma membrane; integral to membrane;
ERGIC2	5	endoplasmic reticulum membrane; Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; Golgi vesicle transport;
ERGIC3	5	endoplasmic reticulum membrane; Golgi apparatus; endoplasmic reticulum-Golgi intermediate compartment membrane; integral to membrane; Golgi vesicle transport;
LMAN2L	5	endoplasmic reticulum membrane; Golgi apparatus; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi vesicle transport;
RAB2A	5	endoplasmic reticulum membrane; endoplasmic reticulum-Golgi intermediate compartment membrane; melanosome; ER to Golgi vesicle-mediated transport; Golgi vesicle transport;
SORT1	5	endoplasmic reticulum membrane; Golgi apparatus; plasma membrane; integral to membrane; trans-Golgi network transport vesicle;
COPB2	5	Golgi apparatus; intracellular protein transport; retrograde vesicle-mediated transport, Golgi to ER; Golgi vesicle transport; COPI coating of Golgi vesicle;
GBF1	5	Golgi apparatus; cis-Golgi network; retrograde vesicle-mediated transport, Golgi to ER; Golgi vesicle transport; COPI coating of Golgi vesicle;
GOLGA5	5	Golgi apparatus; cis-Golgi network; integral to membrane; Golgi organization; Golgi vesicle transport;
GOSR1	5	Golgi apparatus; cis-Golgi network; ER to Golgi vesicle-mediated transport; integral to membrane; Golgi vesicle transport;

Genes shared at least 2 KEGG pathways with TMED10 (count: 0)

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Region: chr14:75598171..75643349 View in gBrowse