ADHDgene Database

Gene Report

Basic Info

Approved Symbol	TUT1
Previous Symbol	RBM21
Symbol Alias	FLJ22347, FLJ22267, FLJ21850, PAPD2, TUTase
Approved Name	terminal uridylyl transferase 1, U6 snRNA-specific
Previous Name	RNA binding motif protein 21
Name Alias	RNA uridylyltransferase, "U6 TUTase"
Location	11q12.2
Position	chr11:62342180-62359649, -
External Links	HGNC: 26184 Entrez Gene: 64852 Ensembl: ENSG00000149016 UCSC: uc001nto.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0071044	histone mRNA catabolic process	Biological Process	IMP[18172165]	2
GO:0050265	RNA uridylyltransferase activity	Molecular Function	IDA[18288197]	1
GO:0019899	enzyme binding	Molecular Function	IPI[18305108]	47
GO:0016607	nuclear speck	Cellular Component	IDA[18288197]	34
GO:0016180	snRNA processing	Biological Process	IMP[16790842]	3
GO:0008270	zinc ion binding	Molecular Function		323
GO:0006379	mRNA cleavage	Biological Process		4
GO:0006378	mRNA polyadenylation	Biological Process	IMP[18288197]	2
GO:0005730	nucleolus	Cellular Component	IDA[16790842]	243
GO:0005847	mRNA cleavage and polyadenylation specificity factor complex	Cellular Component	IDA[18305108]	2
GO:0005515	protein binding	Molecular Function	IPI[18288197]	910
GO:0005524	ATP binding	Molecular Function		228
GO:0003730	mRNA 3'-UTR binding	Molecular Function		7
GO:0004652	polynucleotide adenylyltransferase activity	Molecular Function	IDA[18288197]	1
GO:0003723	RNA binding	Molecular Function	IDA[18288197]	104

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with TUT1 (count: 3)

Gene Symbol	Pathway Count	Pathway List
RBM4	6	nuclear speck; zinc ion binding; nucleolus; protein binding; mRNA 3'-UTR binding; RNA binding;
U2AF1	5	nuclear speck; zinc ion binding; nucleolus; protein binding; RNA binding;
CPSF3	5	mRNA cleavage; mRNA polyadenylation; mRNA cleavage and polyadenylation specificity factor complex; protein binding; RNA binding;

Genes shared at least 2 KEGG pathways with TUT1 (count: 0)

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Region: chr11:62342180..62359649 View in gBrowse