ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0001525
Name	angiogenesis
Type	Biological Process
No. of Genes in ADHDgene	35
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 35)

Literature-origin genes (count: 6)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
NRXN1	neurexin 1	2p16.3	1(0/1/0)
VEGFA	vascular endothelial growth factor A	6p12	1(0/1/0)	IDA[11427521]
ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	12q23	2(2/0/0)
ADRA2B	adrenergic, alpha-2B-, receptor	2q11.1	1(1/0/0)
FGF10	fibroblast growth factor 10	5p13-p12	1(0/1/0)
EREG	epiregulin	4q21.21	1(0/0/1)

Genes from other sources (count: 29)

Approved Symbol	Approved Name	Source	Evidence[PMID]
FN1	fibronectin 1	Mapped by significant region
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	Mapped by CNV
RTN4	reticulon 4	Mapped by CNV
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	Mapped by significant region	IGI[15849270]
THY1	Thy-1 cell surface antigen	Mapped by significant region
VEGFB	vascular endothelial growth factor B	Mapped by significant region
TBX1	T-box 1	Mapped by CNV
HOXA3	homeobox A3	Mapped by significant region	IEP[17972163]
HOXA7	homeobox A7	Mapped by significant region	IEP[17972163]
HOXB3	homeobox B3	Mapped by LD-proxy	IEP[17972163]
PRKD1	protein kinase D1	Mapped by significant region
TGFBR1	transforming growth factor, beta receptor 1	Mapped by significant region
IL18	interleukin 18 (interferon-gamma-inducing factor)	Mapped by significant region	IDA[11466388]
AAMP	angio-associated, migratory cell protein	Mapped by significant region	NAS[10329261]
COL8A1	collagen, type VIII, alpha 1	Mapped by CNV
SYK	spleen tyrosine kinase	Mapped by significant region
PLCD1	phospholipase C, delta 1	Mapped by PBA pathway
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	Mapped by CNV
SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6	Mapped by CNV	NAS[10187864]
PDCD10	programmed cell death 10	Mapped by CNV
FGF9	fibroblast growth factor 9 (glia-activating factor)	Mapped by significant region
JAM3	junctional adhesion molecule 3	Mapped by significant region
CTGF	connective tissue growth factor	Mapped by significant region
GJA5	gap junction protein, alpha 5, 40kDa	Mapped by CNV	IEP[11866539]
ADAM8	ADAM metallopeptidase domain 8	Mapped by CNV; Mapped by LD-proxy
NUS1	nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)	Mapped by significant region
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway
COL15A1	collagen, type XV, alpha 1	Mapped by significant region
STAB2	stabilin 2	Mapped by LD-proxy	NAS[12077138]