ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005874
Name	microtubule
Type	Cellular Component
No. of Genes in ADHDgene	52
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 52)

Literature-origin genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
CLASP2	cytoplasmic linker associated protein 2	3p24.3	1(0/0/1)
DNM1	dynamin 1	9q34	1(0/0/1)
MAP1B	microtubule-associated protein 1B	5q13	1(0/0/1)

Genes from other sources (count: 49)

Approved Symbol	Approved Name	Source	Evidence[PMID]
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	Mapped by PBA pathway
MAPRE1	microtubule-associated protein, RP/EB family, member 1	Mapped by PBA pathway	IDA[10773885]
CDK5RAP2	CDK5 regulatory subunit associated protein 2	Mapped by significant region	IDA[19553473]
DNAH10	dynein, axonemal, heavy chain 10	Mapped by CNV
MAP7	microtubule-associated protein 7	Mapped by PBA pathway; Mapped by significant region
INVS	inversin	Mapped by significant region
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	Mapped by significant region
MAP6	microtubule-associated protein 6	Mapped by significant region	IDA[17210638]
TUBGCP6	tubulin, gamma complex associated protein 6	Mapped by PBA pathway
MAPRE2	microtubule-associated protein, RP/EB family, member 2	Mapped by significant region
HOOK3	hook homolog 3 (Drosophila)	Mapped by PBA pathway
KIF23	kinesin family member 23	Mapped by PBA pathway
MAP1S	microtubule-associated protein 1S	Mapped by PBA pathway	IDA[15528209]
TUBA3D	tubulin, alpha 3d	Mapped by CNV; Mapped by significant region
TUBA4A	tubulin, alpha 4a	Mapped by significant region
NDE1	nudE nuclear distribution gene E homolog 1 (A. nidulans)	Mapped by CNV; Mapped by significant region
DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	Mapped by LD-proxy; Mapped by significant region
WDR47	WD repeat domain 47	Mapped by CNV
TUBA3E	tubulin, alpha 3e	Mapped by significant region
STMN1	stathmin 1	Mapped by PBA pathway
CEP57	centrosomal protein 57kDa	Mapped by significant region	IDA[12717444]
DYNLRB2	dynein, light chain, roadblock-type 2	Mapped by significant region
TUBA4B	tubulin, alpha 4b (pseudogene)	Mapped by significant region
DNAH11	dynein, axonemal, heavy chain 11	Mapped by significant region
KATNB1	katanin p80 (WD repeat containing) subunit B 1	Mapped by PBA pathway
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	Mapped by significant region
DNAI2	dynein, axonemal, intermediate chain 2	Mapped by CNV
KIFC1	kinesin family member C1	Mapped by LD-proxy
MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))	Mapped by PBA pathway
TPPP	tubulin polymerization promoting protein	Mapped by PBA pathway	IDA[18028908]
INCENP	inner centromere protein antigens 135/155kDa	Mapped by significant region
DNAH3	dynein, axonemal, heavy chain 3	Mapped by significant region
KIF11	kinesin family member 11	Mapped by PBA pathway
MAP3K11	mitogen-activated protein kinase kinase kinase 11	Mapped by significant region	IDA[12529434]
TUBB3	tubulin, beta 3	Mapped by significant region
KLC2	kinesin light chain 2	Mapped by significant region
NEK6	NIMA (never in mitosis gene a)-related kinase 6	Mapped by significant region
GAS8	growth arrest-specific 8	Mapped by significant region	IDA[10969087]
EML3	echinoderm microtubule associated protein like 3	Mapped by significant region
KIF12	kinesin family member 12	Mapped by significant region
CENPJ	centromere protein J	Mapped by PBA pathway
TUBGCP4	tubulin, gamma complex associated protein 4	Mapped by LD-proxy
KIF19	kinesin family member 19	Mapped by CNV
IQGAP2	IQ motif containing GTPase activating protein 2	Mapped by CNV
MAPT	microtubule-associated protein tau	Mapped by LD-proxy; Mapped by PBA pathway
TUBGCP5	tubulin, gamma complex associated protein 5	Mapped by PBA pathway; Mapped by significant region
KIF1C	kinesin family member 1C	Mapped by PBA pathway
MAP1A	microtubule-associated protein 1A	Mapped by LD-proxy
KIF22	kinesin family member 22	Mapped by CNV