ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0007596
Name	blood coagulation
Type	Biological Process
No. of Genes in ADHDgene	83
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 83)

Literature-origin genes (count: 12)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ADRA2A	adrenergic, alpha-2A-, receptor	10q24-q26	12(4/8/0)
SLC7A10	solute carrier family 7, (neutral amino acid transporter, y+ system) member 10	19q13.1	1(1/0/0)
ARRB1	arrestin, beta 1	11q13	2(1/1/0)
ADRA2C	adrenergic, alpha-2C-, receptor	4p16.3	7(2/4/1)
ARRB2	arrestin, beta 2	17p13	1(1/0/0)
ATP2B3	ATPase, Ca++ transporting, plasma membrane 3	Xq28	1(0/1/0)
NOS1	nitric oxide synthase 1 (neuronal)	12q14-qter	1(1/0/0)
ADRA2B	adrenergic, alpha-2B-, receptor	2q11.1	1(1/0/0)
VEGFA	vascular endothelial growth factor A	6p12	1(0/1/0)
DGKH	diacylglycerol kinase, eta	13q13.3	1(1/0/0)
PRKG1	protein kinase, cGMP-dependent, type I	10q11.2	1(0/0/1)
PTPRJ	protein tyrosine phosphatase, receptor type, J	11p11.2	1(0/1/0)

Genes from other sources (count: 71)

Approved Symbol	Approved Name	Source	Evidence[PMID]
KIF22	kinesin family member 22	Mapped by CNV
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	Mapped by LD-proxy
MAPK3	mitogen-activated protein kinase 3	Mapped by CNV
ZFPM1	zinc finger protein, multitype 1	Mapped by significant region
CFL1	cofilin 1 (non-muscle)	Mapped by significant region
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	Mapped by significant region
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	Mapped by significant region
ADORA2A	adenosine A2a receptor	Mapped by CNV	TAS[10899090]
RAB27A	RAB27A, member RAS oncogene family	Mapped by LD-proxy
DOCK8	dedicator of cytokinesis 8	Mapped by CNV
ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	Mapped by LD-proxy; Mapped by literature SNP
MGLL	monoglyceride lipase	Mapped by PBA pathway
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	Mapped by significant region
KIF23	kinesin family member 23	Mapped by PBA pathway
CABLES1	Cdk5 and Abl enzyme substrate 1	Mapped by significant region
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	Mapped by significant region
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	Mapped by CNV
SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	Mapped by CNV
SYK	spleen tyrosine kinase	Mapped by significant region
APOA1	apolipoprotein A-I	Mapped by significant region
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	Mapped by significant region
LMAN1	lectin, mannose-binding, 1	Mapped by LD-proxy; Mapped by PBA pathway; Mapped by significant region	TAS[9546392]
JAM3	junctional adhesion molecule 3	Mapped by significant region
WDR1	WD repeat domain 1	Mapped by CNV
KIF2C	kinesin family member 2C	Mapped by PBA pathway
SH2B3	SH2B adaptor protein 3	Mapped by LD-proxy
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	Mapped by significant region
SLC7A5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	Mapped by significant region
ORAI1	ORAI calcium release-activated calcium modulator 1	Mapped by PBA pathway
DAGLA	diacylglycerol lipase, alpha	Mapped by significant region
SPN	sialophorin	Mapped by CNV
F7	coagulation factor VII (serum prothrombin conversion accelerator)	Mapped by CNV
STXBP3	syntaxin binding protein 3	Mapped by CNV
TUBA4A	tubulin, alpha 4a	Mapped by significant region
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	Mapped by significant region
GATA6	GATA binding protein 6	Mapped by significant region
KIFC1	kinesin family member C1	Mapped by LD-proxy
VEGFB	vascular endothelial growth factor B	Mapped by significant region
TRPC6	transient receptor potential cation channel, subfamily C, member 6	Mapped by significant region
ALDOA	aldolase A, fructose-bisphosphate	Mapped by CNV
KDM1A	lysine (K)-specific demethylase 1A	Mapped by LD-proxy
F2RL2	coagulation factor II (thrombin) receptor-like 2	Mapped by PBA pathway
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	Mapped by CNV
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region
JMJD1C	jumonji domain containing 1C	Mapped by PBA pathway
GP1BB	glycoprotein Ib (platelet), beta polypeptide	Mapped by CNV
FN1	fibronectin 1	Mapped by significant region
EHD1	EH-domain containing 1	Mapped by significant region
PDE2A	phosphodiesterase 2A, cGMP-stimulated	Mapped by significant region
ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	Mapped by CNV
KIF11	kinesin family member 11	Mapped by PBA pathway
KLC2	kinesin light chain 2	Mapped by significant region
F10	coagulation factor X	Mapped by CNV	IC[17469850]
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy
ESAM	endothelial cell adhesion molecule	Mapped by significant region
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	Mapped by significant region
AKAP10	A kinase (PRKA) anchor protein 10	Mapped by significant region
PRKCB	protein kinase C, beta	Mapped by significant region
POTEKP	POTE ankyrin domain family, member K, pseudogene	Mapped by significant region
HABP4	hyaluronan binding protein 4	Mapped by significant region
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	Mapped by CNV
RASGRP2	RAS guanyl releasing protein 2 (calcium and DAG-regulated)	Mapped by significant region
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	Mapped by significant region
HBG2	hemoglobin, gamma G	Mapped by CNV
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	Mapped by significant region
STX4	syntaxin 4	Mapped by CNV
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	Mapped by CNV
PRCP	prolylcarboxypeptidase (angiotensinase C)	Mapped by significant region
AMICA1	adhesion molecule, interacts with CXADR antigen 1	Mapped by significant region
EHD3	EH-domain containing 3	Mapped by CNV
TRPC3	transient receptor potential cation channel, subfamily C, member 3	Mapped by PBA pathway