ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0008134
Name	transcription factor binding
Type	Molecular Function
No. of Genes in ADHDgene	38
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 38)

Literature-origin genes (count: 7)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
LMO4	LIM domain only 4	1p22.3	1(0/1/0)
ARRB1	arrestin, beta 1	11q13	2(1/1/0)	IPI[16325578]
HES1	hairy and enhancer of split 1, (Drosophila)	3q28-q29	1(1/0/0)	NAS[17611704]
HES6	hairy and enhancer of split 6 (Drosophila)	2q37.3	1(0/1/0)	NAS[17611704]
FOXP2	forkhead box P2	7q31	1(1/0/0)
FOXP1	forkhead box P1	3p14.1	1(0/0/1)
MEIS2	Meis homeobox 2	15q14	1(0/0/1)

Genes from other sources (count: 31)

Approved Symbol	Approved Name	Source	Evidence[PMID]
DAXX	death-domain associated protein	Mapped by LD-proxy; Mapped by PBA pathway	IDA[10698492]
DRAP1	DR1-associated protein 1 (negative cofactor 2 alpha)	Mapped by significant region
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	Mapped by CNV
IGHMBP2	immunoglobulin mu binding protein 2	Mapped by CNV; Mapped by significant region	IPI[19299493]
HEY2	hairy/enhancer-of-split related with YRPW motif 2	Mapped by significant region	NAS[17611704]
HMGA1	high mobility group AT-hook 1	Mapped by PBA pathway	IDA[10428834]
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	Mapped by PBA pathway
FOXL1	forkhead box L1	Mapped by significant region
ZFPM1	zinc finger protein, multitype 1	Mapped by significant region	IPI[12483298]
HOXA7	homeobox A7	Mapped by significant region	IPI[18973687]
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	Mapped by significant region	IPI[10849440]
AIP	aryl hydrocarbon receptor interacting protein	Mapped by significant region	TAS[9447995]
MED1	mediator complex subunit 1	Mapped by LD-proxy; Mapped by PBA pathway	IPI[17641689]
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	Mapped by significant region	NAS[10698492]
KDM1A	lysine (K)-specific demethylase 1A	Mapped by LD-proxy
SORBS3	sorbin and SH3 domain containing 3	Mapped by PBA pathway
E2F5	E2F transcription factor 5, p130-binding	Mapped by CNV	IPI[16360038]
FOXF1	forkhead box F1	Mapped by significant region
MAPK9	mitogen-activated protein kinase 9	Mapped by CNV	IDA[10376527]
FOXG1	forkhead box G1	Mapped by significant region
KCTD1	potassium channel tetramerisation domain containing 1	Mapped by significant region	IPI[19115315]
NAAA	N-acylethanolamine acid amidase	Mapped by CNV
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	Mapped by PBA pathway	IPI[14701856]
RNF19A	ring finger protein 19A	Mapped by PBA pathway	TAS[10976766]
FOXD4	forkhead box D4	Mapped by CNV
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	Mapped by significant region
FOXR1	forkhead box R1	Mapped by significant region
FOXE1	forkhead box E1 (thyroid transcription factor 2)	Mapped by significant region
STK36	serine/threonine kinase 36	Mapped by significant region	IDA[10806483]
GATA6	GATA binding protein 6	Mapped by significant region	IPI[15016828]