ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0030054
Name cell junction
Type Cellular Component
No. of Genes in ADHDgene  77
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 77)

Literature-origin genes (count: 24)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SYT2 synaptotagmin II 1q32.1 1(1/0/0)
MAP1B microtubule-associated protein 1B 5q13 1(0/0/1)
GRID2 glutamate receptor, ionotropic, delta 2 4q22 1(0/0/1)
NRXN1 neurexin 1 2p16.3 1(0/1/0)
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 15q24 1(0/1/0)
DACT1 dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis) 14q22.3 1(0/1/0)
GRIK1 glutamate receptor, ionotropic, kainate 1 21q22 1(0/0/1)
SYN3 synapsin III 22q12.3 1(0/1/0)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 15q13.3 2(0/1/1)
GRIK4 glutamate receptor, ionotropic, kainate 4 11q 1(0/1/0)
STX1A syntaxin 1A (brain) 7q11.2 3(2/1/0)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 20 7(4/3/0)
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A 11q23.1-q23.2 1(0/1/0)
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0)
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 3(1/2/0)
SYP synaptophysin Xp11.23-p11.22 3(3/0/0)
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 18(13/5/0)
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 4p12 1(0/0/1)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 17pter-p12 2(0/2/0)
SNPH syntaphilin 20p13 1(1/0/0)
CPLX4 complexin 4 18q21.32 1(1/0/0)
SYT1 synaptotagmin I 12cen-q21 4(2/2/0)
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12p12 1(1/0/0)

Genes from other sources Help (count: 53)

Approved Symbol Approved Name Source Evidence[PMID]
FERMT3 fermitin family member 3 Mapped by significant region
P2RX6 purinergic receptor P2X, ligand-gated ion channel, 6 Mapped by CNV IDA[12088286]
EPB41L2 erythrocyte membrane protein band 4.1-like 2 Mapped by significant region
TJP1 tight junction protein 1 (zona occludens 1) Mapped by CNV; Mapped by significant region
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 Mapped by PBA pathway
SYT12 synaptotagmin XII Mapped by significant region
SYT10 synaptotagmin X Mapped by CNV
CHRNB4 cholinergic receptor, nicotinic, beta 4 Mapped by LD-proxy
DOC2A double C2-like domains, alpha Mapped by CNV
ARHGAP32 Rho GTPase activating protein 32 Mapped by significant region
UNC13C unc-13 homolog C (C. elegans) Mapped by CNV
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 Mapped by significant region
SYT9 synaptotagmin IX Mapped by CNV
SNAP29 synaptosomal-associated protein, 29kDa Mapped by CNV
SYT7 synaptotagmin VII Mapped by significant region
EGFLAM EGF-like, fibronectin type III and laminin G domains Mapped by significant region
NLGN1 neuroligin 1 Mapped by CNV
CHRNA5 cholinergic receptor, nicotinic, alpha 5 Mapped by LD-proxy
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Mapped by CNV; Mapped by significant region
SYT4 synaptotagmin IV Mapped by significant region
CNIH2 cornichon homolog 2 (Drosophila) Mapped by significant region
SHANK2 SH3 and multiple ankyrin repeat domains 2 Mapped by significant region
CBLN3 cerebellin 3 precursor Mapped by significant region
RAPSN receptor-associated protein of the synapse Mapped by LD-proxy
DTNA dystrobrevin, alpha Mapped by significant region
HMCN1 hemicentin 1 Mapped by significant region
ACHE acetylcholinesterase Mapped by PBA pathway
CHRM1 cholinergic receptor, muscarinic 1 Mapped by PBA pathway; Mapped by significant region
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 Mapped by CNV; Mapped by significant region
SNAP23 synaptosomal-associated protein, 23kDa Mapped by PBA pathway
TRPV1 transient receptor potential cation channel, subfamily V, member 1 Mapped by PBA pathway
PERP PERP, TP53 apoptosis effector Mapped by significant region
CYFIP2 cytoplasmic FMR1 interacting protein 2 Mapped by significant region
MUSK muscle, skeletal, receptor tyrosine kinase Mapped by significant region
ZNRF1 zinc and ring finger 1 Mapped by significant region
VWC2L von Willebrand factor C domain containing protein 2-like Mapped by significant region
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 Mapped by CNV; Mapped by significant region
GOPC golgi-associated PDZ and coiled-coil motif containing Mapped by significant region
DLG2 discs, large homolog 2 (Drosophila) Mapped by significant region
CHRM5 cholinergic receptor, muscarinic 5 Mapped by CNV; Mapped by PBA pathway
AMOTL1 angiomotin like 1 Mapped by significant region
GPR142 G protein-coupled receptor 142 Mapped by CNV
CYFIP1 cytoplasmic FMR1 interacting protein 1 Mapped by significant region
SIGMAR1 sigma non-opioid intracellular receptor 1 Mapped by LD-proxy
TBC1D2 TBC1 domain family, member 2 Mapped by significant region
GRIA4 glutamate receptor, ionotrophic, AMPA 4 Mapped by significant region
SV2C synaptic vesicle glycoprotein 2C Mapped by CNV
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region
DENND1A DENN/MADD domain containing 1A Mapped by significant region
PRRT2 proline-rich transmembrane protein 2 Mapped by CNV
CHRM3 cholinergic receptor, muscarinic 3 Mapped by CNV; Mapped by PBA pathway
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014