ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0042981
Name	regulation of apoptotic process
Type	Biological Process
No. of Genes in ADHDgene	32
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 32)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	9q34	20(11/9/0)
DUSP1	dual specificity phosphatase 1	5q35.1	1(0/1/0)
UNC5B	unc-5 homolog B (C. elegans)	10q22.2	1(0/0/1)
CAMK1D	calcium/calmodulin-dependent protein kinase ID	10p13	1(0/0/1)
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	11p11.2	1(0/0/1)

Genes from other sources (count: 27)

Approved Symbol	Approved Name	Source	Evidence[PMID]
BCAR1	breast cancer anti-estrogen resistance 1	Mapped by significant region	TAS[11607844]
TGFBR1	transforming growth factor, beta receptor 1	Mapped by significant region	IDA[18758450]
UBC	ubiquitin C	Mapped by CNV
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	Mapped by significant region
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	Mapped by significant region
TRAF1	TNF receptor-associated factor 1	Mapped by significant region	IDA[10692572]
CARD6	caspase recruitment domain family, member 6	Mapped by significant region
SGK1	serum/glucocorticoid regulated kinase 1	Mapped by significant region
RTN4	reticulon 4	Mapped by CNV	NAS[11126360]
CARD18	caspase recruitment domain family, member 18	Mapped by significant region
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	Mapped by significant region
CASP5	caspase 5, apoptosis-related cysteine peptidase	Mapped by significant region
CARD17	caspase recruitment domain family, member 17	Mapped by significant region
CARD16	caspase recruitment domain family, member 16	Mapped by significant region
ACTN3	actinin, alpha 3	Mapped by significant region	NAS[16807302]
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	Mapped by significant region	IDA[12819136]
IL6	interleukin 6 (interferon, beta 2)	Mapped by significant region	IDA[9949178]
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	Mapped by significant region	NAS[12567487]
DUSP2	dual specificity phosphatase 2	Mapped by LD-proxy
PSMA8	proteasome (prosome, macropain) subunit, alpha type, 8	Mapped by significant region
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	Mapped by significant region
CD3G	CD3g molecule, gamma (CD3-TCR complex)	Mapped by significant region	IMP[12407027]
UBB	ubiquitin B	Mapped by significant region
KIAA1324	KIAA1324	Mapped by CNV
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	Mapped by significant region
PSMG2	proteasome (prosome, macropain) assembly chaperone 2	Mapped by CNV
NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	Mapped by CNV