ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0006917
Name	induction of apoptosis
Type	Biological Process
No. of Genes in ADHDgene	31
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 31)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
PHLDA1	pleckstrin homology-like domain, family A, member 1	12q15	1(0/1/0)

Genes from other sources (count: 30)

Approved Symbol	Approved Name	Source	Evidence[PMID]
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	Mapped by significant region
NDUFS3	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	Mapped by LD-proxy	IMP[16826196]
DAXX	death-domain associated protein	Mapped by LD-proxy; Mapped by PBA pathway
C5	complement component 5	Mapped by significant region
ERN2	endoplasmic reticulum to nucleus signaling 2	Mapped by significant region	IMP[11175748]
PDCD7	programmed cell death 7	Mapped by PBA pathway	ISS[10037816]
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	Mapped by significant region	IDA[15705586]
DFNA5	deafness, autosomal dominant 5	Mapped by CNV; Mapped by significant region
TGFBR1	transforming growth factor, beta receptor 1	Mapped by significant region
C22orf29	chromosome 22 open reading frame 29	Mapped by CNV
BAD	BCL2-associated agonist of cell death	Mapped by significant region	IDA[19667065]
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	Mapped by significant region	IDA[9266972]
PYCARD	PYD and CARD domain containing	Mapped by CNV	TAS[10567338]
CIDEB	cell death-inducing DFFA-like effector b	Mapped by significant region	IDA[12429024]
CASP4	caspase 4, apoptosis-related cysteine peptidase	Mapped by significant region	TAS[7743998]
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	Mapped by CNV	IDA[9396766]
PERP	PERP, TP53 apoptosis effector	Mapped by significant region
RIPK3	receptor-interacting serine-threonine kinase 3	Mapped by significant region
SMNDC1	survival motor neuron domain containing 1	Mapped by PBA pathway	TAS[9817934]
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	Mapped by LD-proxy
TPD52L1	tumor protein D52-like 1	Mapped by significant region	IDA[14761963]
BCLAF1	BCL2-associated transcription factor 1	Mapped by significant region	TAS[10330179]
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	Mapped by significant region	TAS[8391931]
RPS3	ribosomal protein S3	Mapped by significant region	IDA[14988002]
DPF2	D4, zinc and double PHD fingers family 2	Mapped by significant region	TAS[8812431]
INHA	inhibin, alpha	Mapped by significant region	IDA[8267637]
MAPK1	mitogen-activated protein kinase 1	Mapped by LD-proxy	TAS[10958679]
WWOX	WW domain containing oxidoreductase	Mapped by significant region
EI24	etoposide induced 2.4 mRNA	Mapped by significant region
AIFM3	apoptosis-inducing factor, mitochondrion-associated, 3	Mapped by CNV	IDA[15764604]