ADHDgene Database
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  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005730
Name nucleolus
Type Cellular Component
No. of Genes in ADHDgene  243
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 243)

Literature-origin genes (count: 17)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0)
PHLDA1 pleckstrin homology-like domain, family A, member 1 12q15 1(0/1/0)
TDP2 tyrosyl-DNA phosphodiesterase 2 6p22.3-p22.1 1(0/1/0)
HOXB1 homeobox B1 17q21.32 1(0/0/1)
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0)
MOBP myelin-associated oligodendrocyte basic protein 3p21.33 1(0/0/1)
HK1 hexokinase 1 10q22 1(0/1/0)
CLOCK clock homolog (mouse) 4q12 2(2/0/0)
HKDC1 hexokinase domain containing 1 10q22.1 1(0/1/0)
FOXP1 forkhead box P1 3p14.1 1(0/0/1)
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 2p25 1(0/1/0)
ATXN2 ataxin 2 12q23-q24.1 1(0/0/1)
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae) 6p21.1-p12.3 1(0/0/1)
XPO1 exportin 1 (CRM1 homolog, yeast) 2p15 1(0/0/1)
NPAS3 neuronal PAS domain protein 3 14q12-q13 1(1/0/0)
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2) 12q23 2(2/0/0)
ATXN1 ataxin 1 6p23 1(0/0/1)

Genes from other sources Help (count: 226)

Approved Symbol Approved Name Source Evidence[PMID]
TACC2 transforming, acidic coiled-coil containing protein 2 Mapped by PBA pathway
HOXA3 homeobox A3 Mapped by significant region
RPL35 ribosomal protein L35 Mapped by significant region TAS[2891103]
ZNF77 zinc finger protein 77 Mapped by CNV
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific Mapped by significant region IDA[16790842]
ZBTB20 zinc finger and BTB domain containing 20 Mapped by LD-proxy
HOXA2 homeobox A2 Mapped by significant region
PHF2 PHD finger protein 2 Mapped by significant region
CRBN cereblon Mapped by CNV
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 Mapped by PBA pathway
KLHL20 kelch-like 20 (Drosophila) Mapped by significant region
RFWD2 ring finger and WD repeat domain 2 Mapped by significant region
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) Mapped by CNV
AP3B2 adaptor-related protein complex 3, beta 2 subunit Mapped by PBA pathway
CDK12 cyclin-dependent kinase 12 Mapped by LD-proxy
KLHL7 kelch-like 7 (Drosophila) Mapped by significant region
EPB41L2 erythrocyte membrane protein band 4.1-like 2 Mapped by significant region
FLII flightless I homolog (Drosophila) Mapped by significant region
DDX52 DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 Mapped by CNV
AATF apoptosis antagonizing transcription factor Mapped by CNV
TCF25 transcription factor 25 (basic helix-loop-helix) Mapped by significant region
IMP4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) Mapped by significant region IDA[12655004]
OASL 2'-5'-oligoadenylate synthetase-like Mapped by PBA pathway IDA[9826176]
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 Mapped by significant region
REXO2 REX2, RNA exonuclease 2 homolog (S. cerevisiae) Mapped by significant region
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 Mapped by PBA pathway IDA[12466272]
SMC1A structural maintenance of chromosomes 1A Mapped by PBA pathway
STX16 syntaxin 16 Mapped by PBA pathway
SRP19 signal recognition particle 19kDa Mapped by LD-proxy IDA[10618370]
ZBTB9 zinc finger and BTB domain containing 9 Mapped by LD-proxy
MPHOSPH6 M-phase phosphoprotein 6 Mapped by significant region
BSPRY B-box and SPRY domain containing Mapped by significant region
POLA2 polymerase (DNA directed), alpha 2 (70kD subunit) Mapped by significant region
KRT18 keratin 18 Mapped by PBA pathway
TEX10 testis expressed 10 Mapped by significant region
SYVN1 synovial apoptosis inhibitor 1, synoviolin Mapped by significant region
SNX15 sorting nexin 15 Mapped by significant region
OSBPL1A oxysterol binding protein-like 1A Mapped by significant region
ZC3H18 zinc finger CCCH-type containing 18 Mapped by significant region
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney) Mapped by significant region
VWA5A von Willebrand factor A domain containing 5A Mapped by significant region
POLD3 polymerase (DNA-directed), delta 3, accessory subunit Mapped by significant region
DPF2 D4, zinc and double PHD fingers family 2 Mapped by significant region
BRIX1 BRX1, biogenesis of ribosomes, homolog (S. cerevisiae) Mapped by significant region
PRC1 protein regulator of cytokinesis 1 Mapped by PBA pathway
DPP3 dipeptidyl-peptidase 3 Mapped by significant region
MED4 mediator complex subunit 4 Mapped by PBA pathway
TRIM5 tripartite motif containing 5 Mapped by CNV
ZBTB34 zinc finger and BTB domain containing 34 Mapped by significant region
TUBGCP2 tubulin, gamma complex associated protein 2 Mapped by CNV; Mapped by LD-proxy; Mapped by PBA pathway; Mapped by literature SNP
SNW1 SNW domain containing 1 Mapped by PBA pathway
ZNF74 zinc finger protein 74 Mapped by CNV
NF2 neurofibromin 2 (merlin) Mapped by PBA pathway IDA[9537418]
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) Mapped by significant region
SLC30A5 solute carrier family 30 (zinc transporter), member 5 Mapped by significant region
RILPL1 Rab interacting lysosomal protein-like 1 Mapped by CNV
NUMA1 nuclear mitotic apparatus protein 1 Mapped by significant region
GSTT2B glutathione S-transferase theta 2B (gene/pseudogene) Mapped by CNV
SUB1 SUB1 homolog (S. cerevisiae) Mapped by significant region
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 Mapped by significant region
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 Mapped by CNV
RPS25 ribosomal protein S25 Mapped by significant region IDA[10050887]
GSTT2 glutathione S-transferase theta 2 Mapped by CNV
ASRGL1 asparaginase like 1 Mapped by significant region
FAM71B family with sequence similarity 71, member B Mapped by significant region
FHOD3 formin homology 2 domain containing 3 Mapped by significant region
RAD23B RAD23 homolog B (S. cerevisiae) Mapped by significant region
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8 Mapped by PBA pathway
SERGEF secretion regulating guanine nucleotide exchange factor Mapped by LD-proxy
STXBP3 syntaxin binding protein 3 Mapped by CNV
MAML1 mastermind-like 1 (Drosophila) Mapped by CNV
HINT3 histidine triad nucleotide binding protein 3 Mapped by significant region
NCAPG2 non-SMC condensin II complex, subunit G2 Mapped by CNV
API5 apoptosis inhibitor 5 Mapped by PBA pathway
CELF4 CUGBP, Elav-like family member 4 Mapped by significant region
SART1 squamous cell carcinoma antigen recognized by T cells Mapped by significant region
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) Mapped by significant region
TAOK2 TAO kinase 2 Mapped by CNV
DHX15 DEAH (Asp-Glu-Ala-His) box polypeptide 15 Mapped by CNV; Mapped by PBA pathway
MEN1 multiple endocrine neoplasia I Mapped by significant region
GPSM2 G-protein signaling modulator 2 Mapped by CNV
RAD1 RAD1 homolog (S. pombe) Mapped by significant region
DHX9 DEAH (Asp-Glu-Ala-His) box polypeptide 9 Mapped by significant region
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) Mapped by LD-proxy
HINFP histone H4 transcription factor Mapped by significant region IDA[11553631]
SAP18 Sin3A-associated protein, 18kDa Mapped by significant region
MPHOSPH8 M-phase phosphoprotein 8 Mapped by significant region
PRPF4 PRP4 pre-mRNA processing factor 4 homolog (yeast) Mapped by significant region
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mapped by CNV; Mapped by significant region
DCPS decapping enzyme, scavenger Mapped by significant region
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) Mapped by CNV
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 Mapped by LD-proxy
ZNF367 zinc finger protein 367 Mapped by significant region
SCAF8 SR-related CTD-associated factor 8 Mapped by LD-proxy; Mapped by literature SNP
SLC29A2 solute carrier family 29 (nucleoside transporters), member 2 Mapped by significant region TAS[7639753]
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa Mapped by CNV
AIP aryl hydrocarbon receptor interacting protein Mapped by significant region
DAXX death-domain associated protein Mapped by LD-proxy; Mapped by PBA pathway
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) Mapped by CNV; Mapped by significant region
STX5 syntaxin 5 Mapped by significant region
GPRC5B G protein-coupled receptor, family C, group 5, member B Mapped by significant region
YPEL4 yippee-like 4 (Drosophila) Mapped by significant region
SETD1A SET domain containing 1A Mapped by CNV
YPEL3 yippee-like 3 (Drosophila) Mapped by CNV
DGCR8 DiGeorge syndrome critical region gene 8 Mapped by CNV
U2AF1 U2 small nuclear RNA auxiliary factor 1 Mapped by PBA pathway
SLU7 SLU7 splicing factor homolog (S. cerevisiae) Mapped by PBA pathway; Mapped by significant region
NUSAP1 nucleolar and spindle associated protein 1 Mapped by PBA pathway
RAD9A RAD9 homolog A (S. pombe) Mapped by significant region
IARS isoleucyl-tRNA synthetase Mapped by significant region
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme Mapped by significant region
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa Mapped by significant region
FAM129A family with sequence similarity 129, member A Mapped by significant region
CAPG capping protein (actin filament), gelsolin-like Mapped by PBA pathway
POU2F3 POU class 2 homeobox 3 Mapped by significant region
TNR tenascin R (restrictin, janusin) Mapped by significant region
HSF2 heat shock transcription factor 2 Mapped by significant region
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor) Mapped by LD-proxy
SCAMP2 secretory carrier membrane protein 2 Mapped by PBA pathway
KAT5 K(lysine) acetyltransferase 5 Mapped by significant region IDA[16387653]
HYLS1 hydrolethalus syndrome 1 Mapped by significant region
EFTUD2 elongation factor Tu GTP binding domain containing 2 Mapped by PBA pathway
ZNF263 zinc finger protein 263 Mapped by LD-proxy
SPATA13 spermatogenesis associated 13 Mapped by CNV
RCHY1 ring finger and CHY zinc finger domain containing 1 Mapped by CNV
CABIN1 calcineurin binding protein 1 Mapped by CNV
CENPW centromere protein W Mapped by significant region
ZNF259 zinc finger protein 259 Mapped by significant region
CEP164 centrosomal protein 164kDa Mapped by significant region
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV
SF3B2 splicing factor 3b, subunit 2, 145kDa Mapped by PBA pathway; Mapped by significant region
STAP1 signal transducing adaptor family member 1 Mapped by significant region
SF3A3 splicing factor 3a, subunit 3, 60kDa Mapped by PBA pathway
MTA2 metastasis associated 1 family, member 2 Mapped by significant region
TSEN15 tRNA splicing endonuclease 15 homolog (S. cerevisiae) Mapped by significant region
ALKBH8 alkB, alkylation repair homolog 8 (E. coli) Mapped by significant region
SNAP29 synaptosomal-associated protein, 29kDa Mapped by CNV
TARDBP TAR DNA binding protein Mapped by literature SNP
HNF1B HNF1 homeobox B Mapped by CNV
MS4A1 membrane-spanning 4-domains, subfamily A, member 1 Mapped by significant region
RCC1 regulator of chromosome condensation 1 Mapped by PBA pathway
RPS9 ribosomal protein S9 Mapped by CNV IDA[18420587]
SF1 splicing factor 1 Mapped by PBA pathway; Mapped by significant region
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated Mapped by significant region
SF3A1 splicing factor 3a, subunit 1, 120kDa Mapped by PBA pathway
DROSHA drosha, ribonuclease type III Mapped by significant region
ACBD6 acyl-CoA binding domain containing 6 Mapped by significant region
CEP57 centrosomal protein 57kDa Mapped by significant region
LRRCC1 leucine rich repeat and coiled-coil domain containing 1 Mapped by CNV
RNF2 ring finger protein 2 Mapped by significant region
TSPYL1 TSPY-like 1 Mapped by significant region
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae) Mapped by CNV
NCOA6 nuclear receptor coactivator 6 Mapped by PBA pathway
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 Mapped by PBA pathway
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Mapped by PBA pathway
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4 Mapped by significant region
CDC14B CDC14 cell division cycle 14 homolog B (S. cerevisiae) Mapped by significant region IDA[18662541]
TMEM109 transmembrane protein 109 Mapped by significant region
FOXD4 forkhead box D4 Mapped by CNV
NFRKB nuclear factor related to kappaB binding protein Mapped by significant region
ZMAT5 zinc finger, matrin-type 5 Mapped by PBA pathway
MED1 mediator complex subunit 1 Mapped by LD-proxy; Mapped by PBA pathway IDA[16314496]
SSRP1 structure specific recognition protein 1 Mapped by significant region
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 Mapped by CNV; Mapped by PBA pathway; Mapped by significant region
NCF2 neutrophil cytosolic factor 2 Mapped by significant region
MTA3 metastasis associated 1 family, member 3 Mapped by LD-proxy; Mapped by literature SNP
PSPC1 paraspeckle component 1 Mapped by significant region
MTG1 mitochondrial GTPase 1 homolog (S. cerevisiae) Mapped by CNV
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) Mapped by CNV
CENPV centromere protein V Mapped by significant region
INO80E INO80 complex subunit E Mapped by CNV
EIF6 eukaryotic translation initiation factor 6 Mapped by LD-proxy
APRT adenine phosphoribosyltransferase Mapped by significant region
NCOR2 nuclear receptor corepressor 2 Mapped by CNV
ZFP91 zinc finger protein 91 homolog (mouse) Mapped by significant region
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) Mapped by significant region
RBM4 RNA binding motif protein 4 Mapped by significant region IDA[12628928]
MUS81 MUS81 endonuclease homolog (S. cerevisiae) Mapped by significant region
INO80C INO80 complex subunit C Mapped by significant region
FUS fused in sarcoma Mapped by CNV
BCL9L B-cell CLL/lymphoma 9-like Mapped by significant region
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 Mapped by significant region
WDR74 WD repeat domain 74 Mapped by significant region IDA[12429849]
PERP PERP, TP53 apoptosis effector Mapped by significant region
CHD1L chromodomain helicase DNA binding protein 1-like Mapped by CNV
RBM14 RNA binding motif protein 14 Mapped by significant region
ZFR zinc finger RNA binding protein Mapped by significant region
BCLAF1 BCL2-associated transcription factor 1 Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy
ELMOD1 ELMO/CED-12 domain containing 1 Mapped by significant region
NMD3 NMD3 homolog (S. cerevisiae) Mapped by CNV
RSPH4A radial spoke head 4 homolog A (Chlamydomonas) Mapped by significant region
CRYM crystallin, mu Mapped by significant region
THRSP thyroid hormone responsive Mapped by significant region
RNF20 ring finger protein 20 Mapped by significant region IDA[19037095]
NOP10 NOP10 ribonucleoprotein homolog (yeast) Mapped by CNV
COG5 component of oligomeric golgi complex 5 Mapped by CNV
CDCA7L cell division cycle associated 7-like Mapped by significant region
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) Mapped by CNV; Mapped by significant region
HOXA11 homeobox A11 Mapped by significant region
ELP2 elongation protein 2 homolog (S. cerevisiae) Mapped by significant region IC[11714725]
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast) Mapped by CNV
COG3 component of oligomeric golgi complex 3 Mapped by PBA pathway
THRAP3 thyroid hormone receptor associated protein 3 Mapped by PBA pathway
HSPA8 heat shock 70kDa protein 8 Mapped by significant region
CCDC86 coiled-coil domain containing 86 Mapped by significant region
RBPJ recombination signal binding protein for immunoglobulin kappa J region Mapped by CNV IDA[9874765]
BCAS2 breast carcinoma amplified sequence 2 Mapped by PBA pathway
PGR progesterone receptor Mapped by significant region
C16orf46 chromosome 16 open reading frame 46 Mapped by significant region
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein Mapped by significant region IDA[11714725]
G2E3 G2/M-phase specific E3 ubiquitin protein ligase Mapped by significant region
SDHAF2 succinate dehydrogenase complex assembly factor 2 Mapped by significant region
RBMXL2 RNA binding motif protein, X-linked-like 2 Mapped by CNV
NOL10 nucleolar protein 10 Mapped by significant region
NOL4 nucleolar protein 4 Mapped by significant region
NOL8 nucleolar protein 8 Mapped by significant region
SNAP23 synaptosomal-associated protein, 23kDa Mapped by PBA pathway
TMUB1 transmembrane and ubiquitin-like domain containing 1 Mapped by LD-proxy; Mapped by literature SNP
USP28 ubiquitin specific peptidase 28 Mapped by significant region
FEN1 flap structure-specific endonuclease 1 Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region
RNF40 ring finger protein 40 Mapped by CNV
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1 Mapped by significant region
RBM4B RNA binding motif protein 4B Mapped by significant region
C16orf88 chromosome 16 open reading frame 88 Mapped by significant region
CDCA5 cell division cycle associated 5 Mapped by significant region

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Last update: Feb 26, 2014