ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0045211
Name postsynaptic membrane
Type Cellular Component
No. of Genes in ADHDgene  41
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 41)

Literature-origin genes (count: 15)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A 11q23.1-q23.2 1(0/1/0)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 15q24 1(0/1/0)
GRM7 glutamate receptor, metabotropic 7 3p26-p25 1(1/0/0)
GRID2 glutamate receptor, ionotropic, delta 2 4q22 1(0/0/1)
ARRB2 arrestin, beta 2 17p13 1(1/0/0)
LIN7C lin-7 homolog C (C. elegans) 11p14 1(1/0/0)
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 16p13.2 3(1/2/0)
GABRG1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 4p12 1(0/0/1)
GRIK1 glutamate receptor, ionotropic, kainate 1 21q22 1(0/0/1)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 20 7(4/3/0)
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10q21 1(0/1/0)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 15q13.3 2(0/1/1)
GRIK4 glutamate receptor, ionotropic, kainate 4 11q 1(0/1/0)
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B 11q23.1 3(1/2/0)
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 12p12 1(1/0/0)

Genes from other sources Help (count: 26)

Approved Symbol Approved Name Source Evidence[PMID]
SHANK2 SH3 and multiple ankyrin repeat domains 2 Mapped by significant region
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region
CHRNB4 cholinergic receptor, nicotinic, beta 4 Mapped by LD-proxy
RAPSN receptor-associated protein of the synapse Mapped by LD-proxy
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3 Mapped by CNV; Mapped by significant region
CHRM1 cholinergic receptor, muscarinic 1 Mapped by PBA pathway; Mapped by significant region
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion Mapped by significant region
TRPV1 transient receptor potential cation channel, subfamily V, member 1 Mapped by PBA pathway
PICALM phosphatidylinositol binding clathrin assembly protein Mapped by significant region
GABRG3 gamma-aminobutyric acid (GABA) A receptor, gamma 3 Mapped by CNV; Mapped by significant region
CHRM3 cholinergic receptor, muscarinic 3 Mapped by CNV; Mapped by PBA pathway
ARHGAP32 Rho GTPase activating protein 32 Mapped by significant region
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 Mapped by significant region
CHRM5 cholinergic receptor, muscarinic 5 Mapped by CNV; Mapped by PBA pathway
ADORA2A adenosine A2a receptor Mapped by CNV
CLSTN2 calsyntenin 2 Mapped by CNV
GOPC golgi-associated PDZ and coiled-coil motif containing Mapped by significant region
DLG2 discs, large homolog 2 (Drosophila) Mapped by significant region
CNIH2 cornichon homolog 2 (Drosophila) Mapped by significant region
CHRNA5 cholinergic receptor, nicotinic, alpha 5 Mapped by LD-proxy
CACNG5 calcium channel, voltage-dependent, gamma subunit 5 Mapped by PBA pathway
ACHE acetylcholinesterase Mapped by PBA pathway
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 Mapped by CNV; Mapped by significant region
GRIA4 glutamate receptor, ionotrophic, AMPA 4 Mapped by significant region
NLGN1 neuroligin 1 Mapped by CNV
MUSK muscle, skeletal, receptor tyrosine kinase Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014