ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

GO Report

Basic Info

ID	GO:0006470
Name	protein dephosphorylation
Type	Biological Process
No. of Genes in ADHDgene	18
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 18)

Literature-origin genes (count: 2)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
DUSP1	dual specificity phosphatase 1	5q35.1	1(0/1/0)
PTPRN2	protein tyrosine phosphatase, receptor type, N polypeptide 2	7q36	1(0/0/1)	TAS[8798755]

Genes from other sources (count: 16)

Approved Symbol	Approved Name	Source	Evidence[PMID]
MTMR2	myotubularin related protein 2	Mapped by significant region	NAS[9736772]
PPM1K	protein phosphatase, Mg2+/Mn2+ dependent, 1K	Mapped by CNV
PTPRD	protein tyrosine phosphatase, receptor type, D	Mapped by CNV	TAS[7896816]
PPEF2	protein phosphatase, EF-hand calcium binding domain 2	Mapped by CNV	TAS[9326663]
DUSP12	dual specificity phosphatase 12	Mapped by CNV
PTPMT1	protein tyrosine phosphatase, mitochondrial 1	Mapped by LD-proxy
PTPN3	protein tyrosine phosphatase, non-receptor type 3	Mapped by significant region	IDA[10364224]
PTPRK	protein tyrosine phosphatase, receptor type, K	Mapped by CNV; Mapped by significant region	IDA[16263724]
CTDSP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1	Mapped by significant region	IDA[12721286]
DUSP2	dual specificity phosphatase 2	Mapped by LD-proxy
PTPN18	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	Mapped by significant region	TAS[8950995]
PPP6C	protein phosphatase 6, catalytic subunit	Mapped by significant region	IDA[16716191]
SSH3	slingshot homolog 3 (Drosophila)	Mapped by significant region
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	Mapped by significant region	IMP[18662541]; NAS[9367992]
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	Mapped by significant region
PTPN14	protein tyrosine phosphatase, non-receptor type 14	Mapped by literature SNP	TAS[7733990]