ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Other Variant Report

Basic Info

Name	DRD4_promoter_-616C/G
Type	point mutation
Location	promoter
Related Gene	DRD4
No. of Study	5 (significant: 1; non-significant 4; trend: 0)

Variant related studies (count: 5)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Barr CL, 2001(d)	C/G		allelic P-value=0.154, X²=2.036 allelic P-value=0.154, X²=2.036	there was a trend for the transmission of allele C but this ...... there was a trend for the transmission of allele C but this was also not significant More...	Non-significant
Mill J, 2003	C/G		TRANSMIT P-value>0.05 TRANSMIT P-value>0.05	no evidence of biased transmission to ADHD probands was foun...... no evidence of biased transmission to ADHD probands was found More...	Non-significant
Kirley A, 2004			allelic TDT P-value=0.21, X²=1.86 in combined sub...... allelic TDT P-value=0.21, X²=1.86 in combined subtype More...	there was no association between this variant and DSM-IV com...... there was no association between this variant and DSM-IV combined type ADHD More...	Non-significant
Kereszturi E, 2007	C/G			No association was found between ADHD and this SNP No association was found between ADHD and this SNP	Non-significant
Lowe N, 2004 (a)	C/G		TDT P-value=0.008, OR=1.63, 95% CI=1.16-2.38 TDT P-value=0.008, OR=1.63, 95% CI=1.16-2.38	significant over transmission significant over transmission	Significant