ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa04810
Name Regulation of actin cytoskeleton
No. of Genes in ADHDgene  48
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 48)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 17p11.2 2(1/1/0)
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0)
TIAM2 T-cell lymphoma invasion and metastasis 2 6q25 1(0/0/1)
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0)
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 17p13 1(0/0/1)
ITGA11 integrin, alpha 11 15q22.3-q23 1(0/0/1)
ITGA1 integrin, alpha 1 5q11.1 1(0/1/0)

Genes from other sources Help(count: 41)

Approved Symbol Approved Name Location Source
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 16p13.1-p11 Mapped by CNV
FGF4 fibroblast growth factor 4 11q13.3 Mapped by significant region
FGF9 fibroblast growth factor 9 (glia-activating factor) 13q11-q12 Mapped by significant region
ACTN3 actinin, alpha 3 11q13-q14 Mapped by significant region
FN1 fibronectin 1 2q34 Mapped by significant region
TMSB4Y thymosin beta 4, Y-linked Y Mapped by PBA pathway
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
APC adenomatous polyposis coli 5q21-q22 Mapped by LD-proxy; Mapped by PBA pathway
CYFIP1 cytoplasmic FMR1 interacting protein 1 15q11 Mapped by significant region
CYFIP2 cytoplasmic FMR1 interacting protein 2 5q34 Mapped by significant region
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 16p11.2 Mapped by CNV
RDX radixin 11q23 Mapped by significant region
BDKRB2 bradykinin receptor B2 14q32.1-q32.2 Mapped by PBA pathway
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 11q13 Mapped by significant region
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 20p12 Mapped by CNV
BCAR1 breast cancer anti-estrogen resistance 1 16q22-q23 Mapped by significant region
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 22q11.21 Mapped by CNV
CHRM3 cholinergic receptor, muscarinic 3 1q41-q44 Mapped by CNV; Mapped by PBA pathway
PDGFD platelet derived growth factor D 11q22.3 Mapped by significant region
CHRM5 cholinergic receptor, muscarinic 5 15q26 Mapped by CNV; Mapped by PBA pathway
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 2p24 Mapped by significant region
GSN gelsolin 9q33 Mapped by PBA pathway; Mapped by significant region
CHRM1 cholinergic receptor, muscarinic 1 11q12-q13 Mapped by PBA pathway; Mapped by significant region
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 11q13-q14 Mapped by significant region
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
WASL Wiskott-Aldrich syndrome-like 7q31.3 Mapped by CNV
ARPC5L actin related protein 2/3 complex, subunit 5-like 9q34.11 Mapped by significant region
CFL1 cofilin 1 (non-muscle) 11q13.1 Mapped by significant region
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 1q Mapped by significant region
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 5q13.1 Mapped by significant region
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 2q36.1 Mapped by significant region
PIK3CG phosphoinositide-3-kinase, catalytic, gamma polypeptide 7q22 Mapped by CNV
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4 2q22 Mapped by CNV; Mapped by significant region
SSH3 slingshot homolog 3 (Drosophila) 11q13 Mapped by significant region
FGF3 fibroblast growth factor 3 11q13 Mapped by significant region
FGF19 fibroblast growth factor 19 11q13.1 Mapped by significant region
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 11q23.3 Mapped by significant region
FGD3 FYVE, RhoGEF and PH domain containing 3 9q22 Mapped by significant region
IQGAP2 IQ motif containing GTPase activating protein 2 5q Mapped by CNV
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 5q11.2 Mapped by LD-proxy
INS insulin 11p15.5 Mapped by literature SNP

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014