ADHDgene Database
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Type:
  • Large-scale studies
  • Data Summary
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa05152
Name Tuberculosis
Description  Tuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent infections, and about 10% of latent infections develop active diseases when their immune system is impaired due to the age, other diseases such as AIDS or exposure to immunosuppressive drugs. TB is transmitted through the air and primarily attacks the lungs, then it can spread by the circulatory system to other parts of body. Once TB bacilli have entered the host by the respiratory route and infected macrophages in the lungs, they interfere with phagosomal maturation, antigen presentation, apoptosis and host immune system to establish persistent or latent infection.
No. of Genes in ADHDgene  30
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 30)

Literature-origin genes (count: 1)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 6p21.3 2(1/1/0)

Genes from other sources Help(count: 29)

Approved Symbol Approved Name Location Source
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 18q21 Mapped by significant region
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 5q31.1-q33.1 Mapped by significant region
CAMK2D calcium/calmodulin-dependent protein kinase II delta 4q26 Mapped by CNV
IL10RA interleukin 10 receptor, alpha 11q23 Mapped by significant region
CYCS cytochrome c, somatic 7p21.2 Mapped by CNV; Mapped by significant region
MAPK1 mitogen-activated protein kinase 1 22q11.2 Mapped by LD-proxy
IL18 interleukin 18 (interferon-gamma-inducing factor) 11q22.2-q22.3 Mapped by significant region
IL6 interleukin 6 (interferon, beta 2) 7p21-p15 Mapped by significant region
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 11q13 Mapped by significant region
TLR4 toll-like receptor 4 9q33.1 Mapped by significant region
BAD BCL2-associated agonist of cell death 11q13.1 Mapped by significant region
SYK spleen tyrosine kinase 9q22 Mapped by significant region
PPP3R2 protein phosphatase 3, regulatory subunit B, beta 9q31 Mapped by significant region
IFNGR1 interferon gamma receptor 1 6q23-q24 Mapped by significant region
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2 12q24.31 Mapped by CNV
ATP6V0D2 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 8q21.3 Mapped by CNV
MAPK9 mitogen-activated protein kinase 9 5q35 Mapped by CNV
MAPK3 mitogen-activated protein kinase 3 16p11.2 Mapped by CNV
CORO1A coronin, actin binding protein, 1A 16p11.2 Mapped by CNV
FADD Fas (TNFRSF6)-associated via death domain 11q13.3 Mapped by significant region
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 11q24.2 Mapped by significant region
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 1q23 Mapped by CNV
PIK3C3 phosphoinositide-3-kinase, class 3 18q12.3 Mapped by significant region
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 1q23 Mapped by CNV
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 1q23 Mapped by CNV
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) 1q23 Mapped by CNV
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 1q23 Mapped by CNV
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 11q23.3 Mapped by significant region
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 11q13.2 Mapped by significant region

Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014