ADHDgene Database

SNP Report

Basic Info

Name	rs10227331 dbSNP Ensembl
Location	Chr7:157294938(Fwd)
Variant Alleles	T/A
Ancestral Allele	T
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000444158) intron_variant(ENST00000449903) nc_transcript_variant(ENST00000449903)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lasky-Su J, 2008			P-value=3.79E-06 under Recessive model for IA symptom count P-value=3.79E-06 under Recessive model for IA symptom count	association finding with P-value association finding with P-value	Trend

SNP related genes (count: 0)

SNPs in LD with rs10227331 (count: 5) View in gBrowse (chr7:157294938..157300672 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs10237006	downstream_gene_variant	0.822[CEU]; 0.889[TSI]
rs1894811	downstream_gene_variant	0.923[CEU]; 0.827[TSI]
rs2302447	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[YRI]
rs11764996	downstream_gene_variant	0.924[CEU]
rs10807647	downstream_gene_variant	0.822[CEU]; 0.823[TSI]