ADHDgene Database

SNP Report

Basic Info

Name	rs10832876 dbSNP Ensembl
Location	Chr11:18059929(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000417164) intron_variant(ENST00000341556; ENST00000417164; ENST00000250018; ENST00000528338)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Johansson S, 2010			logistic regression P-value=0.17, OR=1.15 logistic regression P-value=0.17, OR=1.15	no significant association no significant association	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
TPH1	tryptophan hydroxylase 1	11p15.3-p14	6(2/4/0)

SNPs in LD with rs10832876 (count: 12) View in gBrowse (chr11:17944125..18096091 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs10488682	5_prime_UTR_variant; intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs2299626	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.863[CEU]
rs7943725	intron_variant; nc_transcript_variant	0.877[CHB]; 0.821[JPT]
rs11024460		0.827[MEX]
rs11024433	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.843[ASW]; 1.0[CEU]; 1.0[MEX]; 0.821[TSI]
rs10832871	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant	0.843[ASW]; 1.0[CEU]; 1.0[MEX]; 0.827[TSI]
rs211105	NMD_transcript_variant; intron_variant	0.843[ASW]; 1.0[CEU]; 1.0[GIH]; 1.0[MEX]; 0.913[MKK]; 0.97[TSI]
rs11024449	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 0.871[GIH]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs11024445	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]
rs11024434	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.953[CEU]
rs172423	NMD_transcript_variant; intron_variant	0.843[ASW]; 1.0[CEU]; 1.0[GIH]; 1.0[MEX]; 0.913[MKK]; 0.97[TSI]
rs17720530	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]