ADHDgene Database

SNP Report

Basic Info

Name	rs10983238 dbSNP Ensembl
Location	Chr9:119333683(Fwd)
Variant Alleles	C/G
Ancestral Allele	C
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000288520; ENST00000341734; ENST00000373986; ENST00000361209; ENST00000361477; ENST00000313400; ENST00000373996; ENST00000423715) nc_transcript_variant(ENST00000423715)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lesch KP, 2008			ANOVA P-value=1.37E-07, Mean of ranks=15 ANOVA P-value=1.37E-07, Mean of ranks=15	one of the top 30 single SNPs located in gene regions (inclu...... one of the top 30 single SNPs located in gene regions (including 100kb of flanking sequences) ranked according to the mean rank calculated across three statistics; annotated by GWAS Catalog More...	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
ASTN2	astrotactin 2	9q33	2(0/0/2)

SNPs in LD with rs10983238 (count: 21) View in gBrowse (chr9:119192516..119452120 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs17220476	intron_variant; upstream_gene_variant	0.936[CEU]
rs888398	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.864[JPT]
rs10983193	intron_variant	0.936[CEU]; 0.846[CHB]
rs10983211	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.864[JPT]
rs10983262	intron_variant	1.0[CEU]; 0.846[CHB]; 0.857[CHD]; 1.0[JPT]; 1.0[MEX]; 0.972[TSI]
rs13302089	intron_variant	0.936[CEU]
rs12376892	intron_variant; nc_transcript_variant; non_coding_exon_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs12156498	intron_variant	0.875[CEU]; 0.81[TSI]
rs10491578	intron_variant	0.936[CEU]; 0.972[TSI]
rs1861883	intron_variant	0.939[CEU]; 0.846[CHB]
rs12005639	intron_variant	0.875[CEU]; 0.846[CHB]; 0.836[TSI]
rs13292335	intron_variant	0.875[CEU]
rs10983260	intron_variant	1.0[CEU]; 0.846[CHB]; 0.901[CHD]; 1.0[JPT]; 1.0[MEX]; 0.972[TSI]
rs10983300	intron_variant	0.936[CEU]
rs12379128	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.894[CHD]; 0.823[GIH]; 0.864[JPT]; 0.921[MEX]; 1.0[TSI]
rs10983243	intron_variant; nc_transcript_variant	1.0[CHB]; 0.823[JPT]
rs12377406	intron_variant	0.939[CEU]; 0.846[CHB]
rs6478237	intron_variant	0.875[CEU]; 0.81[TSI]
rs17292540	downstream_gene_variant; intron_variant	1.0[CEU]; 0.846[CHB]; 0.864[JPT]
rs10983229	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.864[JPT]
rs12115644	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.864[JPT]