ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs11686538 dbSNP Ensembl
Location	Chr2:225818564(Fwd)
Variant Alleles	A/G
Ancestral Allele	A
Functional Annotation	NMD_transcript_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000435582) intron_variant(ENST00000258390; ENST00000471810; ENST00000435582; ENST00000492369) nc_transcript_variant(ENST00000471810; ENST00000492369)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Stergiakouli E., 2012	G/A	G	P=0.0000127, OR=0.74, 95% CI=0.64-0.84 P=0.0000127, OR=0.74, 95% CI=0.64-0.84	One of the top 28 independent SNP in this ADHD GWAS. One of the top 28 independent SNP in this ADHD GWAS.	Trend

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DOCK10	dedicator of cytokinesis 10	2q36.3	1(0/0/1)

Genes from other sources (count: 0)

SNPs in LD with rs11686538 (count: 21) View in gBrowse (chr2:225774390..225831586 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 21)

rs_ID	Functional Annotation	r²[population]
rs6731109	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.804[JPT]
rs6731100	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.872[GIH]; 0.828[MEX]
rs10498170	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs17271608	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.895[JPT]; 1.0[YRI]
rs13024433	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[ASW]; 0.91[CEU]; 0.869[GIH]; 0.875[LWK]; 1.0[MEX]; 0.881[MKK]; 0.97[TSI]
rs10498171	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.893[ASW]; 1.0[CHB]; 1.0[CHD]; 0.921[GIH]; 1.0[JPT]; 0.83[MEX]
rs10498174	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs1395914	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs13018710	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 0.923[GIH]; 1.0[JPT]; 0.83[MEX]
rs13021690	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.893[ASW]; 1.0[CHB]; 1.0[CHD]; 0.974[GIH]; 1.0[JPT]; 0.83[MEX]
rs13016818	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 0.872[GIH]; 1.0[JPT]
rs11679104	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.946[CHB]; 1.0[JPT]
rs17199431	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 0.948[GIH]; 1.0[JPT]; 0.83[MEX]
rs12999154	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.946[CHB]; 1.0[JPT]
rs13021295	NMD_transcript_variant; intron_variant; missense_variant; nc_transcript_variant; non_coding_exon_variant	0.947[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs953945	NMD_transcript_variant; intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[CHD]; 0.923[GIH]; 1.0[JPT]; 0.83[MEX]
rs17271567	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.893[ASW]; 0.923[GIH]; 0.837[JPT]
rs10498172	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.893[ASW]; 1.0[CHB]; 1.0[CHD]; 0.923[GIH]; 1.0[JPT]; 0.83[MEX]
rs7569781	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.945[CHB]; 0.869[CHD]; 0.974[GIH]; 0.888[JPT]; 0.828[MEX]
rs11692992	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.893[ASW]; 1.0[CHB]; 1.0[CHD]; 0.923[GIH]; 1.0[JPT]; 0.83[MEX]
rs1857996	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.821[JPT]