ADHDgene Database

SNP Report

Basic Info

Name	rs11953346 dbSNP Ensembl
Location	Chr5:94141447(Fwd)
Variant Alleles	T/C
Ancestral Allele	T
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000515393; ENST00000312216; ENST00000429576; ENST00000505078; ENST00000508509; ENST00000512425; ENST00000573439; ENST00000575480; ENST00000574707; ENST00000573142; ENST00000577136; ENST00000575385)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Mick E, 2010		C	TDT P-value=1.59E-05 (OR=0.71) TDT P-value=1.59E-05 (OR=0.71)	One of the top 20 associations from genome-wide association ...... One of the top 20 associations from genome-wide association results More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
MCTP1	multiple C2 domains, transmembrane 1	5q15	1(0/1/0)

SNPs in LD with rs11953346 (count: 10) View in gBrowse (chr5:94046205..94190819 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs36727	downstream_gene_variant; intron_variant	0.823[JPT]
rs17084024	intron_variant; nc_transcript_variant	1.0[CHB]
rs11740749	intron_variant; nc_transcript_variant	0.959[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs293061	intron_variant	1.0[CHB]
rs10059194	intron_variant	0.839[CEU]; 1.0[CHB]; 1.0[JPT]
rs153852	intron_variant	0.823[JPT]
rs153851	intron_variant	0.823[JPT]
rs10066070	intron_variant; nc_transcript_variant	0.959[CEU]; 1.0[CHB]; 0.968[GIH]; 1.0[MEX]; 0.859[MKK]; 0.899[TSI]
rs10041551	intron_variant; nc_transcript_variant; non_coding_exon_variant	0.82[ASW]
rs293032	intron_variant	0.82[ASW]; 1.0[CHB]