ADHDgene Database

SNP Report

Basic Info

Name	rs12518844 dbSNP Ensembl
Location	Chr5:37832759(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000326524; ENST00000502572; ENST00000427982; ENST00000510177; ENST00000344622; ENST00000381826; ENST00000515058)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Laurin N, 2008(a)	G/A		P-value=0.852 in the catergorical analysis, P-value>0.05 in ...... P-value=0.852 in the catergorical analysis, P-value>0.05 in the quantitative analysis More...	no significant evidence of association no significant evidence of association	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
GDNF	glial cell derived neurotrophic factor	5p13.1-p12	2(1/1/0)

SNPs in LD with rs12518844 (count: 14) View in gBrowse (chr5:37771881..37833419 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs1549250	intron_variant	1(0/1/0)	0.858[CHD]

rs_ID	Functional Annotation	r²[population]
rs10512667		0.887[MEX]
rs17379007		0.887[MEX]
rs2972933		0.812[GIH]; 0.836[MEX]
rs12521946	intron_variant	1.0[CEU]; 1.0[YRI]
rs10941370	intron_variant	0.952[CHB]; 0.862[CHD]
rs2973062		0.812[GIH]
rs1477359	intron_variant	1.0[CEU]; 1.0[YRI]
rs2972935		0.814[GIH]
rs1110149	intron_variant	1.0[CEU]; 0.923[YRI]
rs17378973		0.833[MEX]
rs2972930		0.811[GIH]; 0.831[MEX]
rs2972938		0.887[MEX]
rs17379771	3_prime_UTR_variant; downstream_gene_variant	0.887[MEX]