ADHDgene Database

SNP Report

Basic Info

Name	rs1331503 dbSNP Ensembl
Location	Chr9:93402517(Fwd)
Variant Alleles	A/T
Ancestral Allele	T
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000375765)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Reif, A., 2011	T/A		P-value=0.0125, OR (allele)=1.27 (A), 95% CI=1.05-1.54 in Ge...... P-value=0.0125, OR (allele)=1.27 (A), 95% CI=1.05-1.54 in German discovery sample; P-value=0.5812, OR (allele)=1.03 (A), 95% CI=0.92-1.17 in IMpACT replication sample; P-value=0.0678, OR (allele)=1.10 (A), 95% CI=0.99-1.22 in pooled data; PDT P-value=0.4245 for allele A in the family-based analysis More...	4 out of 12 investigated SNPs had p<0.05 in the association ...... 4 out of 12 investigated SNPs had p<0.05 in the association test with aADHD. Replication in 1035 aADHD patients and 1381 controls from IMpACT did not show any significant SNP association. More...	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DIRAS2	DIRAS family, GTP-binding RAS-like 2	9q22.32	1(1/0/0)

SNPs in LD with rs1331503 (count: 10) View in gBrowse (chr9:93402190..93436857 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs1412005	upstream_gene_variant	1(1/0/0)	0.955[CHB]; 0.953[JPT]