ADHDgene Database

SNP Report

Basic Info

Name	rs1430961 dbSNP Ensembl
Location	Chr4:90552920(Fwd)
Variant Alleles	A/G
Ancestral Allele	A
Functional Annotation	intron_variant; nc_transcript_variant.
Consequence to Transcript	intron_variant(ENST00000506864; ENST00000509723; ENST00000508021; ENST00000507916; ENST00000512077) nc_transcript_variant(ENST00000509723; ENST00000506864; ENST00000508021; ENST00000507916; ENST00000512077)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hinney, A., 2011		C	GWAS P-value=1.49E-05, OR=1.76, Replication FBAT P-value=0.6...... GWAS P-value=1.49E-05, OR=1.76, Replication FBAT P-value=0.6698, Combination P-value=3.47E-05 More...	This GWAS in a small group of clinically ascertained young G...... This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	4q21.3-q22	1(0/1/0)

SNPs in LD with rs1430961 (count: 8) View in gBrowse (chr4:90552920..90603419 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs11944530	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.808[YRI]
rs11933399	intron_variant; nc_transcript_variant	1.0[CEU]
rs17015956	intron_variant; nc_transcript_variant	1.0[CHB]; 1.0[JPT]
rs1430960	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs12644119	intron_variant; nc_transcript_variant	0.807[GIH]
rs11932021	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 0.962[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs16996194	intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs11933687	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.965[GIH]; 1.0[JPT]; 1.0[MEX]; 0.952[MKK]; 1.0[TSI]