ADHDgene Database

SNP Report

Basic Info

Name	rs1672717 dbSNP Ensembl
Location	Chr11:113812733(Fwd)
Variant Alleles	G/A
Ancestral Allele	A
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000537778; ENST00000543092; ENST00000260191)
No. of Studies	2 (significant: 2; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Oades RD, 2008			P-value=0.040249; FDR P-value=0.20125 for cognitive impulsiv...... P-value=0.040249; FDR P-value=0.20125 for cognitive impulsivity More...	attained nominal significance for an association with cognit...... attained nominal significance for an association with cognitive impulsivity More...	Significant
Ribases M, 2009(b)			Case-control test: lowest P-value=0.012 for genotype analysi...... Case-control test: lowest P-value=0.012 for genotype analysis, P-value=0.12 for allele analysis in adult combined ADHD. More...	no significance after correcting for multiple comparisons no significance after correcting for multiple comparisons	Significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
HTR3B	5-hydroxytryptamine (serotonin) receptor 3B	11q23.1	3(1/2/0)

SNPs in LD with rs1672717 (count: 8) View in gBrowse (chr11:113770355..113862930 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.


rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]
rs3782025	intron_variant	1(1/0/0)	0.949[CHB]; 0.899[CHD]; 0.887[JPT]