ADHDgene Database

SNP Report

Basic Info

Name	rs17689952 dbSNP Ensembl
Location	Chr4:166939154(Fwd)
Variant Alleles	A/G
Ancestral Allele	A
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000509505) intron_variant(ENST00000509505; ENST00000061240; ENST00000507499; ENST00000513213)
No. of Studies	2 (significant: 0; non-significant: 2; trend: 0)
Source	Literature-origin

SNP related studies (count: 2)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lantieri F, 2010	G:A		Binomial P-value=0.41, OR=0.97 for whole sample; Binomial P-...... Binomial P-value=0.41, OR=0.97 for whole sample; Binomial P-value=0.16, OR=0.85 for C-subtype More...	no significant association no significant association	Non-significant
Neale BM, 2008	G:A		Uncorrected TDT P-value=4.16E-05 (OR=0.7219) Uncorrected TDT P-value=4.16E-05 (OR=0.7219)	One of top 25 results in uncorrected TDT test One of top 25 results in uncorrected TDT test	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location
TLL1	tolloid-like 1	4q32-q33

SNPs in LD with rs17689952 (count: 5) View in gBrowse (chr4:166926573..166948998 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs17633422	NMD_transcript_variant; intron_variant	0.842[CEU]
rs17689892	NMD_transcript_variant; intron_variant	1.0[CEU]; 0.854[CHB]; 0.847[JPT]; 0.801[YRI]
rs17633333	NMD_transcript_variant; intron_variant	0.902[CEU]; 0.819[CHB]; 0.893[JPT]
rs1393857	NMD_transcript_variant; intron_variant	0.849[CHB]; 1.0[JPT]
rs17689964	NMD_transcript_variant; intron_variant	1.0[CEU]