ADHDgene Database

SNP Report

Basic Info

Name	rs2073837 dbSNP Ensembl
Location	Chr9:136522928(Fwd)
Variant Alleles	G/A
Ancestral Allele	A
Functional Annotation	intron_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000393056) upstream_gene_variant(ENST00000425189)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Nyman ES, 2007			Logistic regression for single markers: adjusted for sex: P-...... Logistic regression for single markers: adjusted for sex: P-value=0.0055, OR=2.69, 95%CI=1.34-5.43 for 22vs.11, P-value=0.0099, OR=0.44, 95%CI=0.23-0.82 for 11/12vs.22; Males: P-value=0.0027, OR=5.05, 95%CI=1.75-14.54 for 22vs.11, P-value=0.0036, OR=0.22, 95%CI=0.08-0.61 for 11/12vs.22 More...	The minor homozygote was risk conferring compared with the m...... The minor homozygote was risk conferring compared with the major homozygote adjusted for sex and an even stronger effect was seen in males More...	Significant

SNP related genes (count: 3)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
DBH	dopamine beta-hydroxylase (dopamine beta-monooxygenase)	9q34	20(11/9/0)

Approved Symbol	Approved Name	Location
DBH-AS1	DBH antisense RNA 1 [MODEL Refseq, miscRNA]	9q34.2
NCRNA00118	non-protein coding RNA 118	9q34.2

SNPs in LD with rs2073837 (count: 6) View in gBrowse (chr9:136522187..136532183 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs129915	downstream_gene_variant; upstream_gene_variant	0.851[CEU]
rs129888	downstream_gene_variant	0.899[CEU]
rs2073836	intron_variant; nc_transcript_variant; non_coding_exon_variant	0.949[CEU]
rs129928	downstream_gene_variant	0.899[CEU]
rs1611131	intron_variant; nc_transcript_variant; splice_region_variant	0.946[CEU]
rs2073835	intron_variant; nc_transcript_variant; non_coding_exon_variant	0.949[CEU]