ADHDgene Database

SNP Report

Basic Info

Name	rs2291567 dbSNP Ensembl
Location	Chr7:128483227(Fwd)
Variant Alleles	T/C
Ancestral Allele	C
Functional Annotation	downstream_gene_variant; intron_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000388853) intron_variant(ENST00000346177; ENST00000325888)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	T:C		GLM P-value=1.97E-06, meta-analysis P-value=0.04204 GLM P-value=1.97E-06, meta-analysis P-value=0.04204	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
FLNC	filamin C, gamma	7q32-q35	1(0/0/1)

SNPs in LD with rs2291567 (count: 7) View in gBrowse (chr7:128472981..128511024 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	#studies(significant/non-significant/trend)	r²[population]

rs3734973	downstream_gene_variant; synonymous_variant	1(0/0/1)	1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 0.972[GIH]; 1.0[JPT]; 1.0[MEX]; 0.823[MKK]; 1.0[TSI]
rs13227216	intron_variant; nc_transcript_variant	1(0/1/0)	1.0[CHB]; 0.976[CHD]; 0.838[GIH]; 1.0[JPT]; 0.9[MEX]; 0.808[TSI]

rs_ID	Functional Annotation	r²[population]
rs1472146	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.953[JPT]
rs6970221	downstream_gene_variant; intron_variant; nc_transcript_variant	0.822[CHB]; 0.859[JPT]
rs13226115	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs1994765	intron_variant	0.908[CHB]
rs1472147	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CHB]; 0.929[CHD]; 1.0[JPT]; 0.852[MEX]; 0.851[TSI]