ADHDgene Database

SNP Report

Basic Info

Name	rs3760201 dbSNP Ensembl
Location	Chr17:21193618(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	NMD_transcript_variant; intron_variant; nc_transcript_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000395491; ENST00000479129; ENST00000496046; ENST00000483928) intron_variant(ENST00000395491; ENST00000496046; ENST00000534743; ENST00000479129; ENST00000526076; ENST00000342679; ENST00000361818; ENST00000316920; ENST00000529517; ENST00000483928; ENST00000583508) nc_transcript_variant(ENST00000583508; ENST00000534743)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hinney, A., 2011		T	GWAS P-value=2.05E-05, OR=1.44, Replication FBAT P-value=0.2...... GWAS P-value=2.05E-05, OR=1.44, Replication FBAT P-value=0.2466, Combination P-value=1.84E-05 More...	This GWAS in a small group of clinically ascertained young G...... This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08. More...	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
MAP2K3	mitogen-activated protein kinase kinase 3	17q11.2	1(0/1/0)

SNPs in LD with rs3760201 (count: 8) View in gBrowse (chr17:21172289..21215204 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs9901404	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.87[CHB]; 0.93[CHD]; 0.882[LWK]; 0.849[YRI]
rs1466314	NMD_transcript_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs11652094		0.955[CEU]; 0.863[CHB]; 0.884[CHD]; 1.0[JPT]; 0.913[MEX]; 0.975[TSI]
rs9909362	NMD_transcript_variant; intron_variant; nc_transcript_variant; non_coding_exon_variant; upstream_gene_variant	0.87[CHB]
rs4986003		1.0[CEU]; 0.908[CHB]; 0.906[CHD]; 1.0[JPT]; 0.871[MEX]; 0.974[TSI]
rs6587133		1.0[CEU]; 0.908[CHB]; 0.929[CHD]; 1.0[JPT]; 0.911[MEX]; 0.974[TSI]
rs2001651		0.836[CEU]; 0.908[CHB]; 0.884[CHD]; 1.0[JPT]; 0.956[MEX]
rs959511	upstream_gene_variant	0.912[ASW]; 1.0[CEU]; 0.954[CHB]; 0.976[CHD]; 1.0[JPT]; 0.882[LWK]; 1.0[MEX]; 1.0[TSI]; 0.849[YRI]