ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs3799977 dbSNP Ensembl
Location	Chr6:44837356(Fwd)
Variant Alleles	T/G
Ancestral Allele	T
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000475057) intron_variant(ENST00000475057; ENST00000371460; ENST00000371458; ENST00000371459; ENST00000306867; ENST00000371461)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lesch KP, 2008			ANOVA P-value=4.90E-06, Mean of ranks=80 ANOVA P-value=4.90E-06, Mean of ranks=80	one of the top 30 single SNPs located in gene regions (inclu...... one of the top 30 single SNPs located in gene regions (including 100kb of flanking sequences) ranked according to the mean rank calculated across three statistics; annotated by GWAS Catalog More...	Trend

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	6p21.1-p12.3	1(0/0/1)

Genes from other sources (count: 0)

SNPs in LD with rs3799977 (count: 152) View in gBrowse (chr6:44698708..104757540 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 152)

rs_ID	Functional Annotation	r²[population]
rs12528762	NMD_transcript_variant; intron_variant	0.828[JPT]
rs6925467	NMD_transcript_variant; intron_variant	0.909[CEU]; 1.0[CHB]; 0.944[JPT]
rs2211393		0.891[CHB]
rs12215263	NMD_transcript_variant; intron_variant	1.0[YRI]
rs2894599		0.833[JPT]
rs7742360	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.944[JPT]
rs6910749	downstream_gene_variant	0.942[CHB]
rs12529522	NMD_transcript_variant; intron_variant	0.865[CHD]; 0.887[JPT]
rs1360197	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.881[JPT]
rs9463040		0.836[CHD]
rs9463017		0.836[CHD]
rs3799974	NMD_transcript_variant; intron_variant	0.833[JPT]
rs4714830	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.973[GIH]; 0.885[JPT]; 0.825[LWK]; 1.0[MEX]; 0.822[MKK]; 0.977[TSI]
rs10948190	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.944[JPT]
rs1980265	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.942[JPT]
rs3799968	NMD_transcript_variant; intron_variant	0.891[CHB]; 0.813[CHD]
rs9472376	NMD_transcript_variant; intron_variant	0.866[CHD]; 0.832[JPT]
rs1329716	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.942[JPT]
rs9472360		0.891[CHB]
rs7754378	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.802[GIH]; 1.0[JPT]
rs10948192	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[YRI]
rs720988		0.84[CHD]; 0.833[JPT]
rs4412189	NMD_transcript_variant; intron_variant	0.842[CEU]; 0.944[CHB]; 0.944[JPT]
rs1041332	NMD_transcript_variant; intron_variant	0.9[ASW]; 0.946[CHB]; 0.918[CHD]; 0.944[JPT]; 0.822[MKK]
rs3799979	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs10948183	NMD_transcript_variant; intron_variant	0.808[CEU]; 0.947[CHB]; 0.944[JPT]
rs4398713	NMD_transcript_variant; intron_variant	1.0[CHB]; 1.0[CHD]; 0.944[JPT]; 0.804[MEX]; 0.807[TSI]
rs7769218	NMD_transcript_variant; intron_variant	0.805[JPT]
rs1329710	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CHB]; 1.0[CHD]; 0.885[JPT]; 0.957[MEX]; 0.826[TSI]
rs13211006	NMD_transcript_variant; intron_variant	0.822[JPT]
rs13209827	NMD_transcript_variant; intron_variant	0.828[JPT]
rs9395049	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.946[CHB]; 0.832[JPT]
rs12530016	NMD_transcript_variant; intron_variant	0.866[CHD]; 0.887[JPT]
rs3799965	NMD_transcript_variant; intron_variant	0.865[CHD]; 0.833[JPT]
rs720989		0.866[CHD]; 0.833[JPT]
rs4714825		0.833[JPT]
rs10948198	NMD_transcript_variant; intron_variant	0.842[CEU]; 0.946[CHB]; 0.944[JPT]
rs12208023	NMD_transcript_variant; intron_variant	0.842[CEU]; 0.946[CHB]; 0.918[CHD]; 0.946[GIH]; 0.944[JPT]; 0.84[MEX]; 0.816[MKK]; 0.931[TSI]
rs1521355	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.944[JPT]
rs17422760	NMD_transcript_variant; intron_variant	0.808[CEU]; 0.946[CHB]; 0.972[CHD]; 0.807[GIH]; 1.0[JPT]
rs1028944	NMD_transcript_variant; intron_variant	0.887[CHD]; 0.828[JPT]
rs1329713	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.944[JPT]
rs9472336		0.891[CHB]
rs9357464	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.885[JPT]
rs12528232	NMD_transcript_variant; synonymous_variant	0.892[CHD]; 0.827[JPT]
rs10948194	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.885[JPT]
rs12192367	intron_variant	0.888[CHB]
rs9472409	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.808[CEU]; 0.947[CHB]; 1.0[CHD]; 0.807[GIH]; 0.944[JPT]
rs1418434		0.891[CHB]
rs12214778	NMD_transcript_variant; intron_variant; upstream_gene_variant	1.0[ASW]; 0.917[CEU]; 1.0[CHB]; 1.0[CHD]; 0.944[JPT]; 1.0[MEX]; 0.801[MKK]; 0.931[TSI]
rs227849		0.891[CHB]
rs7763450	NMD_transcript_variant; intron_variant	0.842[CEU]; 0.946[CHB]; 0.944[JPT]
rs7745506	NMD_transcript_variant; intron_variant	0.822[JPT]
rs13206526	NMD_transcript_variant; intron_variant	0.892[CHD]; 0.833[JPT]
rs9472362		0.891[CHB]
rs13201942	NMD_transcript_variant; intron_variant	0.892[CHD]; 0.828[JPT]
rs9472407	NMD_transcript_variant; intron_variant	0.943[CHB]; 0.939[JPT]
rs10948187	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.944[JPT]
rs12190136		0.891[CHB]; 0.881[JPT]
rs12205071	NMD_transcript_variant; intron_variant	0.842[CEU]; 0.946[CHB]; 0.917[CHD]; 0.946[GIH]; 0.944[JPT]; 0.84[MEX]; 0.864[MKK]; 0.93[TSI]
rs4711809	NMD_transcript_variant; intron_variant	0.888[CHB]; 0.807[CHD]
rs3799984	NMD_transcript_variant; intron_variant	1.0[CHB]; 1.0[JPT]
rs3799967	NMD_transcript_variant; intron_variant	0.942[CHB]; 0.876[JPT]
rs3799973	NMD_transcript_variant; intron_variant	0.804[CEU]; 0.942[CHB]; 0.938[JPT]; 0.907[YRI]
rs9367214	NMD_transcript_variant; intron_variant	0.946[CHB]; 0.944[JPT]
rs12526711	NMD_transcript_variant; intron_variant	0.841[CEU]; 0.94[CHB]; 0.94[JPT]
rs35687006	NMD_transcript_variant; intron_variant	0.892[CHD]; 0.822[JPT]
rs2396372	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 0.972[CHD]; 0.921[GIH]; 0.885[JPT]; 1.0[MEX]; 0.977[TSI]; 1.0[YRI]
rs969211	NMD_transcript_variant; intron_variant	0.804[CEU]; 0.946[CHB]; 0.943[JPT]
rs524492	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant	0.866[CHD]; 0.833[JPT]
rs2186062	NMD_transcript_variant; intron_variant	0.839[CEU]; 0.946[CHB]; 0.944[JPT]
rs10948188	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.84[CEU]; 1.0[CHB]; 1.0[CHD]; 0.807[GIH]; 0.89[JPT]
rs929614		0.891[CHB]; 0.828[JPT]
rs12529490	NMD_transcript_variant; intron_variant	0.833[CEU]; 0.893[CHB]; 0.944[JPT]
rs1023091	NMD_transcript_variant; intron_variant	0.828[JPT]
rs4714819		0.884[CHB]
rs9472416	NMD_transcript_variant; intron_variant	0.804[CEU]; 0.945[CHB]; 0.885[JPT]
rs11967188	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.877[JPT]
rs12196818	NMD_transcript_variant; intron_variant	1.0[ASW]; 0.917[CEU]; 1.0[CHB]; 0.972[CHD]; 0.944[JPT]; 0.824[LWK]; 1.0[MEX]; 0.851[MKK]; 0.885[TSI]
rs12190513	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.942[JPT]
rs4714828	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs3799986	NMD_transcript_variant; intron_variant	1.0[CHB]; 1.0[CHD]; 0.944[JPT]; 0.957[MEX]
rs12525009	NMD_transcript_variant; intron_variant	1.0[CEU]; 0.946[CHB]; 0.944[JPT]; 1.0[YRI]
rs2040032		0.891[CHB]
rs542444	NMD_transcript_variant; intron_variant	0.863[CHD]; 0.833[JPT]
rs1418435		0.836[CHD]
rs1971482	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.944[JPT]; 1.0[YRI]
rs3799976	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs16869119	NMD_transcript_variant; intron_variant	0.833[JPT]
rs7749865	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.944[JPT]
rs1360195	NMD_transcript_variant; intron_variant	0.892[CHD]; 0.828[JPT]
rs1329715	NMD_transcript_variant; intron_variant	0.89[CHD]; 0.828[JPT]
rs9369514	3_prime_UTR_variant; NMD_transcript_variant; downstream_gene_variant; intron_variant	0.891[CHB]; 0.82[CHD]; 0.885[JPT]
rs3799972	NMD_transcript_variant; intron_variant	0.833[JPT]
rs9369529	NMD_transcript_variant; intron_variant	0.842[CEU]; 1.0[CHB]; 0.944[JPT]
rs10948176	NMD_transcript_variant; intron_variant	1.0[YRI]
rs10484627	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 0.946[CHB]; 0.972[CHD]; 0.972[GIH]; 1.0[JPT]; 1.0[LWK]; 0.957[MEX]; 1.0[MKK]; 0.977[TSI]; 1.0[YRI]
rs3823252	NMD_transcript_variant; intron_variant	0.889[CHD]; 0.833[JPT]
rs10948197	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 0.921[GIH]; 0.885[JPT]; 1.0[MEX]; 0.977[TSI]
rs13205113	NMD_transcript_variant; intron_variant	0.828[JPT]
rs1293457		0.891[CHB]; 0.828[JPT]
rs2139863	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.833[JPT]
rs4711798		0.891[CHB]
rs7763421	NMD_transcript_variant; intron_variant	0.833[CEU]; 0.93[CHB]; 0.939[JPT]
rs3799987	NMD_transcript_variant; intron_variant; upstream_gene_variant	0.892[CHD]; 0.828[JPT]
rs1342370		0.891[CHB]
rs17424547	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.944[JPT]
rs16872574		0.84[CHD]; 0.833[JPT]
rs636845	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.944[JPT]
rs1293467		0.891[CHB]; 0.819[CHD]; 0.828[JPT]
rs7754698	NMD_transcript_variant; intron_variant	0.885[CHB]
rs6910294	NMD_transcript_variant; intron_variant	0.946[CHB]; 0.884[JPT]
rs1557143		0.891[CHB]; 0.828[JPT]
rs4512220	5_prime_UTR_variant; NMD_transcript_variant; intron_variant	0.828[JPT]
rs9395051	NMD_transcript_variant; intron_variant	0.891[CHB]; 1.0[CHD]; 0.943[JPT]
rs4714834	NMD_transcript_variant; intron_variant	0.892[CHD]; 0.828[JPT]
rs3799971	NMD_transcript_variant; intron_variant	0.891[CHB]; 0.943[JPT]
rs13215618	NMD_transcript_variant; intron_variant	0.804[CEU]; 0.944[CHB]; 0.944[JPT]
rs3778507	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.944[JPT]
rs4714836	NMD_transcript_variant; intron_variant	0.901[ASW]; 0.842[CEU]; 0.946[CHB]; 0.918[CHD]; 0.946[GIH]; 0.944[JPT]; 0.84[MEX]; 0.889[MKK]; 0.931[TSI]
rs1329714	NMD_transcript_variant; intron_variant	0.864[CEU]; 1.0[CHB]; 0.935[JPT]; 0.816[YRI]
rs1023090	NMD_transcript_variant; intron_variant	0.891[CHB]; 0.944[JPT]
rs13216116	NMD_transcript_variant; intron_variant	0.808[CEU]; 1.0[CHB]; 1.0[CHD]; 0.944[JPT]
rs2396371	NMD_transcript_variant; intron_variant	0.943[CHB]; 0.944[JPT]
rs4711799		0.891[CHB]; 0.828[JPT]
rs494982	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 0.944[JPT]
rs9472414	NMD_transcript_variant; intron_variant	0.828[JPT]
rs1338908		0.891[CHB]
rs1159131	NMD_transcript_variant; intron_variant	0.915[CHD]; 0.892[JPT]
rs9369516	NMD_transcript_variant; intron_variant	0.947[CHB]; 1.0[CHD]; 1.0[JPT]
rs3799981	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.944[JPT]
rs4711807	NMD_transcript_variant; intron_variant	1.0[CEU]; 1.0[CHB]; 0.944[JPT]; 1.0[YRI]
rs6458415	NMD_transcript_variant; intron_variant	0.947[CHB]; 0.944[JPT]
rs2396369	NMD_transcript_variant; intron_variant	1.0[CHB]; 1.0[CHD]; 0.944[JPT]
rs538801	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.944[JPT]
rs6904015	NMD_transcript_variant; intron_variant	0.888[CHB]; 0.828[JPT]
rs10948185	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 0.944[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 0.977[TSI]; 1.0[YRI]
rs9367211	NMD_transcript_variant; intron_variant	0.89[CHB]; 0.944[CHD]; 1.0[JPT]
rs6925017	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.872[JPT]
rs976699	NMD_transcript_variant; intron_variant	0.943[CHB]; 0.883[JPT]
rs7775717	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.885[JPT]
rs1402599	NMD_transcript_variant; intron_variant	0.866[CHD]; 0.833[JPT]
rs6919161	NMD_transcript_variant; intron_variant	0.827[JPT]
rs608941	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CHB]; 1.0[CHD]; 0.892[JPT]; 0.957[MEX]; 0.809[MKK]; 0.826[TSI]
rs609643		0.836[CHD]
rs764397		0.891[CHB]
rs2038557		0.891[CHB]
rs10948186	NMD_transcript_variant; intron_variant	1.0[CHB]; 0.944[JPT]
rs2038556		0.891[CHB]
rs9367210	NMD_transcript_variant; intron_variant	1.0[YRI]
rs6924185	NMD_transcript_variant; intron_variant	0.907[YRI]
rs9296450	NMD_transcript_variant; intron_variant	0.892[CHD]