ADHDgene Database

SNP Report

Basic Info

Name	rs4128767 dbSNP Ensembl
Location	Chr15:81543407(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	NMD_transcript_variant; intron_variant.
Consequence to Transcript	NMD_transcript_variant(ENST00000560241; ENST00000360547) intron_variant(ENST00000394660; ENST00000559383; ENST00000559388; ENST00000302987; ENST00000560241; ENST00000360547)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lasky-Su J, 2008			P-value=1.28E-06 under Dominant model for IA symptom count P-value=1.28E-06 under Dominant model for IA symptom count	association finding with P-value association finding with P-value	Trend

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
IL16	interleukin 16 (lymphocyte chemoattractant factor)	15q26.3	1(0/0/1)

SNPs in LD with rs4128767 (count: 8) View in gBrowse (chr15:81476988..81559616 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs12907134	NMD_transcript_variant; intron_variant	0.821[ASW]; 0.87[LWK]; 0.817[YRI]
rs4451910	NMD_transcript_variant; intron_variant	0.814[CHB]
rs1509557	NMD_transcript_variant; downstream_gene_variant; intron_variant	0.814[CHB]
rs12439542	NMD_transcript_variant; intron_variant	0.814[CHB]
rs4589514	NMD_transcript_variant; intron_variant	0.874[CHB]; 0.832[JPT]
rs4344696	NMD_transcript_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 0.943[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[MKK]; 1.0[TSI]; 1.0[YRI]
rs4531696	NMD_transcript_variant; intron_variant	0.844[CEU]; 0.938[CHB]; 0.833[JPT]; 1.0[YRI]
rs4444297	NMD_transcript_variant; intron_variant	0.814[CHB]