ADHDgene Database

SNP Report

Basic Info

Name	rs4374483 dbSNP Ensembl
Location	Chr3:125920064(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	intron_variant(ENST00000502278; ENST00000500232) nc_transcript_variant(ENST00000502278; ENST00000500232) upstream_gene_variant(ENST00000509952; ENST00000511283)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Neale BM, 2010 (b)	A:G		GLM P-value=3.57E-05, meta-analysis P-value=0.07212 GLM P-value=3.57E-05, meta-analysis P-value=0.07212	One of the top 100 SNPs from imputed IMAGE II dataset One of the top 100 SNPs from imputed IMAGE II dataset	Non-significant

SNP related genes (count: 2)

Approved Symbol	Approved Name	Location
ALDH1L1-AS2	ALDH1L1 antisense RNA 2 [VALIDATED Refseq, miscRNA]	3q21.3
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	3q21.2

SNPs in LD with rs4374483 (count: 11) View in gBrowse (chr3:125888991..125942770 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs9871359		0.877[CEU]
rs6782537	NMD_transcript_variant; intron_variant	0.908[JPT]
rs4679218	downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	0.807[CEU]
rs9873750		0.877[CEU]
rs10804575	downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	0.807[CEU]
rs11928458		0.877[CEU]
rs9822040	downstream_gene_variant; nc_transcript_variant; non_coding_exon_variant	0.807[CEU]
rs13326951		0.877[CEU]
rs1447662	intron_variant; nc_transcript_variant; upstream_gene_variant	0.803[CEU]
rs10934756	intron_variant; nc_transcript_variant; upstream_gene_variant	0.807[CEU]
rs12695477	NMD_transcript_variant; intron_variant; nc_transcript_variant	0.81[JPT]