ADHDgene Database

SNP Report

Basic Info

Name	rs4869686 dbSNP Ensembl
Location	Chr5:36679018(Fwd)
Variant Alleles	A/T
Ancestral Allele	T
Functional Annotation	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000505376) intron_variant(ENST00000265113; ENST00000381918; ENST00000427100; ENST00000510740) nc_transcript_variant(ENST00000510740) upstream_gene_variant(ENST00000506178)
No. of Studies	1 (significant: 0; non-significant: 1; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Turic D, 2005(a)	A/T		P-value=0.56 for pooled genotyping P-value=0.56 for pooled genotyping	not significantly associated with ADHD not significantly associated with ADHD	Non-significant

SNP related genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	5p13	2(1/1/0)

SNPs in LD with rs4869686 (count: 8) View in gBrowse (chr5:36662889..36807189 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

rs_ID	Functional Annotation	r²[population]
rs2301065	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]
rs1549627	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]
rs292168		1.0[YRI]
rs2301067	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]
rs2301068	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]; 0.955[CHB]; 1.0[JPT]
rs3756468	downstream_gene_variant; intron_variant; nc_transcript_variant	1.0[YRI]
rs1423677	intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]
rs2301066	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	1.0[CEU]