ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs515910 dbSNP Ensembl
Location	Chr10:105966404(Fwd)
Variant Alleles	A/G
Ancestral Allele	G
Functional Annotation	intron_variant.
Consequence to Transcript	intron_variant(ENST00000278064; ENST00000369720; ENST00000357060; ENST00000369719; ENST00000428666)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Lesch KP, 2008			ANOVA P-value=4.36E-06, Mean of ranks=24 ANOVA P-value=4.36E-06, Mean of ranks=24	one of the top 30 single SNPs located in gene regions (inclu...... one of the top 30 single SNPs located in gene regions (including 100kb of flanking sequences) ranked according to the mean rank calculated across three statistics; annotated by GWAS Catalog More...	Trend

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
WDR96	WD repeat domain 96	10q25.1	1(0/0/1)

Genes from other sources (count: 0)

SNPs in LD with rs515910 (count: 17) View in gBrowse (chr10:105883395..105983356 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 17)

rs_ID	Functional Annotation	r²[population]
rs479879	intron_variant; upstream_gene_variant	0.936[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.974[LWK]; 1.0[MEX]; 0.932[MKK]; 0.978[TSI]; 1.0[YRI]
rs1338777	downstream_gene_variant; intron_variant	0.859[JPT]
rs527154	intron_variant	0.919[CEU]; 0.859[CHB]; 0.908[JPT]; 0.914[YRI]
rs601019	downstream_gene_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.974[LWK]; 1.0[MEX]; 0.932[MKK]; 1.0[TSI]; 1.0[YRI]
rs789970	downstream_gene_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.974[LWK]; 1.0[MEX]; 0.932[MKK]; 1.0[TSI]; 1.0[YRI]
rs686441	downstream_gene_variant; intron_variant; upstream_gene_variant	0.936[ASW]; 1.0[CEU]; 0.859[CHB]; 0.975[CHD]; 1.0[GIH]; 0.953[JPT]; 0.974[LWK]; 1.0[MEX]; 0.932[MKK]; 1.0[TSI]; 1.0[YRI]
rs642743	intron_variant	0.936[ASW]; 1.0[CEU]; 0.815[CHB]; 0.975[CHD]; 0.978[GIH]; 0.908[JPT]; 0.846[LWK]; 1.0[MEX]; 0.919[MKK]; 1.0[TSI]; 0.914[YRI]
rs1147610	intron_variant	1.0[CEU]; 0.859[CHB]; 0.906[JPT]; 0.914[YRI]
rs569967	intron_variant	1.0[CEU]; 0.859[CHB]; 0.908[JPT]; 0.91[YRI]
rs624159	intron_variant	1.0[CEU]; 0.904[CHB]; 0.908[JPT]; 0.912[YRI]
rs678292	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 0.956[YRI]
rs1665241	intron_variant; nc_transcript_variant	0.856[JPT]
rs581686	intron_variant; upstream_gene_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.974[LWK]; 1.0[MEX]; 0.932[MKK]; 1.0[TSI]; 1.0[YRI]
rs584309	intron_variant	0.936[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.923[LWK]; 1.0[MEX]; 0.932[MKK]; 1.0[TSI]; 1.0[YRI]
rs614406	intron_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs556292	downstream_gene_variant; intron_variant	1.0[ASW]; 1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.974[LWK]; 1.0[MEX]; 0.932[MKK]; 1.0[TSI]; 1.0[YRI]
rs677904	intron_variant	1.0[ASW]; 0.96[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 0.974[LWK]; 1.0[MEX]; 0.932[MKK]; 1.0[TSI]; 1.0[YRI]